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　　CCTV News:The Central Meteorological Observatory continued to issue a red rainstorm warning at 10: 00 on July 30. Since July 29, there have been heavy rainstorms in central and southern Hebei, central and southern Beijing, Tianjin, eastern Shanxi, central and northern Henan, and central and western Shandong, heavy rainstorms in parts of central and southern Hebei, northern Henan, eastern Shanxi, and western Shandong, and heavy rainstorms (250-540 mm) in parts of central and southern Hebei, along mountains in central and southern Hebei, and northwest Henan.

　　It is estimated that there will be heavy rainstorms in most parts of Hebei, Beijing, Tianjin, central and eastern Shanxi, northern Henan and western Shandong from 14: 00 on July 30 to 14: 00 on July 31, among which there will be heavy rainstorms in parts of eastern Shanxi, central and southern Hebei and most parts of Beijing, and heavy rainstorms (250-350 mm) in parts of central Hebei and western Beijing. There are heavy rains or rainstorms in central Anhui, eastern Hubei, northwestern Hunan, eastern Fujian, northern and southern Guangxi, southwestern Yunnan, southern Sichuan, southeastern Heilongjiang, northern Jilin and northeastern Xinjiang. Some of the above areas have short-term heavy rainfall (the maximum hourly rainfall is 20 ~ 40 mm, and the local area can exceed 60 mm), and there are strong convective weather such as thunderstorms and strong winds.

　　Defense guide:

　　1, the government and relevant departments in accordance with their duties to do a good job in emergency and rescue work against heavy rain;

　　2. Stop the assembly, suspend classes or business (except for special industries);

　　3, do a good job in mountain torrents, landslides, mudslides and other disasters prevention and rescue work.

Original transfer network transformation medical network

[Introduction] Cancer-associated fibroblasts (CAFs) are the key components of tumor microenvironment (TME) and play an important role in regulating cancer progression. However, the underlying mechanism of CAFs activation is still unclear.

On April 8, researchers from the Medical College of Kunming University of Science and Technology published a research paper in the journal Cell Death Discovery, entitled "CXC L12 Alone is enough to reprogram normal fibers into cancer-associated fibers". In this study, the researchers found that cancer-associated fibroblasts (CAFs) significantly induced normal fibroblasts (NFs) to acquire the characteristics of CAFs (called CAFs-like fibroblasts, referred to as CEFs for short), including up-regulating α-SMA and vimentin, enhancing the ability of proliferation and migration, and improving the ability of promoting the migration of lung cancer cells. In vivo, CEFs accelerated the growth of A549 xenograft and induced spontaneous lung metastasis. In particular, inhibition of CXCL12 signaling pathway and STAT3 pathway can reduce the transformation from NFs to CAFs, thus inhibiting the progress of lung cancer in vitro and in vivo. This study revealed that CAFs can promote the transformation of NFs into CAFs-like cells through CXCL12/STAT3 axis, and enhance the growth and metastasis of lung cancer. Therefore, inhibiting CXCL12/STAT3 axis is a promising strategy for the treatment of lung cancer and other CXCL12-dependent malignant tumors.

https://www.nature.com/articles/s41420-025-02420-0#Abs1

Research background

01

Cancer-associated fibroblasts (CAFs) are the main components of tumor microenvironment (TME), which promote tumor proliferation, migration, invasion, epithelial-mesenchymal transition (EMT) and drug resistance by secreting growth factors, cytokines and extracellular vesicles, thus promoting tumor development. CAFs is a large number of fibroblasts with α -smooth muscle actin (α-SMA) positive and activated myofibroblast phenotype. Different from normal fibroblasts (NFs), CAFs has stronger abilities of proliferation, migration and contraction. It is generally believed that CAFs mainly comes from NFs where organizations reside, but the mechanism of transforming NFs into CAFs is still controversial.

More and more evidences show that cancer-associated fibroblasts (CAFs) can be activated by signals from tumor cells and matrix environment, which provides a unique insight into the complex interaction in tumor ecosystem. Researchers found that the hardness of extracellular matrix (ECM) can induce mesenchymal stem cells (MSCs) to differentiate into CAFs, thus promoting the invasion and metastasis of triple negative breast cancer (TNBC). In addition, in gastric cancer, CAFs can also "educate" NFs to promote cancer cell proliferation and T cell inhibition. However, the exact mechanism that drives CAFs activation is still largely unknown. Therefore, detailed research is needed to clarify the molecular mechanism of cancer-related fibroblast activation, so as to open up a new anti-matrix therapy approach.

CAFs promotes the transformation from NFs to CAFs in lung cancer.

02

In order to explore the clinical effect of tumor-associated fibroblasts (CAFs) in the process of transforming normal fibroblasts (NFs) into CAFs in lung cancer, the researchers isolated pairs of CAFs and NFs from tumor tissues or corresponding non-malignant tissues adjacent to tumors of several lung cancer patients. CAFs specifically shows highly expressed vimentin and FAP (known CAFs markers), and its ability to promote the migration of lung cancer cells is stronger than that of NFs from adjacent tissues. Then, NFs was treated with CAFs conditioned medium (CM), and then the characteristics of CAFs were analyzed. The levels of CAF markers α-SMA and vimentin expressed in NFs after CAFs CM education increased significantly. These results indicate that CAFs may be helpful to endow NFs CAFs with specific characteristics.

CAFs induces NFs to acquire CAFs characteristics in lung cancer

conclusion

03

To sum up, this study expounds a new molecular mechanism that the interaction between NFs and CAFs promotes the metastasis of cancer cells. CXCL12/ STAT3 pathway is a key participant in NFs-to-CAFs transition, which provides a key therapeutic target for developing new cancer treatment methods.

References:

https://www.nature.com/articles/s41420-025-02420-0#Abs1

Original title: "New Molecular Mechanism! Kungong medical college: an important therapeutic target of new cancer treatment strategy

Read the original text

In today’s digital age, banks are constantly introducing innovative authentication methods to improve the security and convenience of services. As a new technology, breath recognition verification is gradually being applied in the banking field. The following is a detailed introduction to how to handle the respiratory identification verification business in the bank.

First, you need to go to the bank’s business outlets. Before you go, it is recommended that you know the business hours of the bank outlets in advance to avoid unnecessary waiting. After arriving at the bank, you can consult the lobby manager about the process and related matters of respiratory identification verification business.

Next, the bank staff will introduce you to the characteristics and advantages of breath recognition verification, and assist you in relevant preparations. Usually, you need to provide valid identity documents to verify your identity information.

During the processing, you will be guided to the special equipment area. These devices are rigorously tested and calibrated to accurately capture your breathing characteristics. When collecting respiratory identification, you need to take deep breaths and breathe steadily according to the prompts of the equipment, so as to ensure that the equipment can obtain accurate and complete respiratory data.

The bank will encrypt and store the collected respiratory data to ensure your information security. At the same time, in order to ensure the accuracy and reliability of verification, you may be required to collect and verify many times.

After the collection of respiratory identification data, the bank will associate and bind your identity information with respiratory characteristics. In the subsequent business processing, when authentication is needed, you only need to breathe according to the prompts, and the system will automatically compare your breathing characteristics, thus quickly completing the authentication.

It should be noted that different banks may have slightly different business processes for breath recognition verification. The following is a list of some common banks for you:

| Name of bank | Characteristics of handling process | Time required | Additional requirements |
|—-|—-|—-|—-|
| Bank A| The process is relatively simple and the equipment is advanced | About 30 minutes | None |
| Bank B| Pay attention to customer guidance and explain in detail | About 45 minutes | You may need to make an appointment in advance |
| Bank C| adopts multiple authentication, with high security | about 1 hour | needs to open specific business |

In a word, it is a relatively simple but very important process to handle the bank breath recognition verification business. It not only brings convenience to your banking business, but also greatly improves the security of your account. I hope the above contents can help you handle this business smoothly.

[Disclaimer] This article only represents the author’s own views and has nothing to do with Hexun. Hexun.com is neutral about the statements and opinions in this article, and does not provide any express or implied guarantee for the accuracy, reliability or completeness of the contents. Readers are requested for reference only, and please take full responsibility. Email: news_center@staff.hexun.com.

　　If you want to defeat the virus, you must understand the virus.

　　As a living body in the micro-world, virus must be supported by science and technology to see through the source of its disease and the principle of its poison and to crack its evolution and transmission mechanism.

The picture shows the virus picture for the Military Medical Research Institute.

　　They are very old — —

　　Appearing in the early days of the origin of life, it is the oldest and most primitive "indigenous people" on the earth.

　　They are tiny — —

　　The biggest virus is only one tenth of the diameter of a hair.

　　They are simple — —

　　It is basically a "genetic material (DNA or RNA)+ protein capsid" model.

The picture shows the personnel of the military medical expert group in the front line of Wuhan’s anti-epidemic. The picture is provided by the Military Medical Research Institute.

　　They are "fragile" — —

　　Can’t live independently, you need to find an ideal host to complete the reproduction and evolution. Once you leave the host, only death awaits them.

　　They are huge — —

　　There are more than 10 bacteriophages (viruses infected with bacteria) in the world’s waters alone. If they are lined up, the total length will reach 200 million light years.

　　They are everywhere — —

　　There are viruses everywhere on the earth where there is life.

　　From sea to land, from plants to animals, from bacteria to fungi … … Even in the human genome, there are virus genome sequences.

　　What causes it is still a mystery.

The picture shows the researchers of Wuhan anti-epidemic frontline processing the samples to be solved. Photo courtesy of Military Medical Research Institute.

　　Fortunately, most viruses are harmless to human beings.

　　So far, only 14 virulent viruses have been found to seriously threaten human life and health, such as smallpox, influenza, hepatitis, AIDS, SARS, Ebola and so on.

　　Usually,The virus only proliferates and spreads in certain kinds of hosts.It is difficult to "move" from one host to another.

　　butWhen some virus mutations accumulate to a certain extentAfter that, it can successfully cross the interspecific barrier of the host, proliferate and spread continuously in the new host, causing the disease and death of the new host, which may lead to an epidemic.

　　The picture shows that the first-line researchers in Wuhan are receiving samples from the Military Medical Research Institute.

　　Looking at the current epidemic situation, emerging infectious diseases have always affected the global nerves.

　　Establishing and perfecting the public health system is the defense strategy for human beings to prevent and control epidemics. Starting from the construction of ecological civilization, it is the fundamental way to achieve coordinated development and harmonious coexistence between man and nature.

　　Author: Xie Lunyu (Associate Professor, School of Applied Economics, Renmin University of China, Director of Institute of Peace and Development)

　　General Secretary of the Supreme Leader emphasized that "if the nation is to be revived, the countryside must be revitalized". The most arduous and arduous task of building a socialist modern country in an all-round way and realizing the great rejuvenation of the Chinese nation is still in the countryside, and the broadest and deepest foundation is still in the countryside. Implementing the rural revitalization strategy is an important historical task to win the victory in building a socialist modern country in an all-round way, and it is also the general grasp of the work of agriculture, rural areas and farmers in the new era. We must fully tap the great potential of rural revitalization in stabilizing economic growth, promoting high-quality development and realizing common prosperity from the height of coordinating the "two overall situations".

　　Accurately grasp the great significance of comprehensively promoting rural revitalization

　　Rural revitalization brings new opportunities for promoting high-quality development. Since the reform and opening up, China has rapidly promoted industrialization and urbanization, continuously improved the efficiency of factor allocation, and released the reform dividend, which has played an important role in creating "two miracles". However, compared with the rapid development of urban development, the development of agriculture, rural areas and farmers has lagged behind. The implementation of rural revitalization strategy plays a vital role in supporting the integrated development of urban and rural areas and promoting the construction of new urbanization, and also provides a new opportunity for the transformation of old and new kinetic energy of China’s economic growth.

　　Rural revitalization brings new opportunities to stabilize macroeconomic fluctuations. In the process of rural revitalization, the improvement of agricultural and rural modernization will create high-quality employment and entrepreneurial opportunities, attract rural talents to return, and play a positive role in stabilizing employment and ensuring income. Rural revitalization will promote the transformation and upgrading of agricultural production mode, change the temporal and spatial pattern of agricultural production and trade, and comprehensively enhance the production and supply capacity of agricultural products, which is of great significance to ensuring the safety of agricultural products supply, stabilizing agricultural products prices and preventing inflation.

　　Rural revitalization opens up a new space for promoting pollution control and realizing the goal of "double carbon". Rural areas are rich in natural resources, which is an important support to improve the supply of ecological products and carbon sink capacity. Rural revitalization encourages areas rich in ecological resources to give full play to their green advantages. It is an important content to promote "peak carbon dioxide emissions, carbon neutrality", realize rural sustainable development and promote the construction of ecological civilization in China by linking five major revitalization with ecological revitalization, exploring the establishment of incentive-compatible ecological product supply and value realization mechanism and accelerating the capitalization of natural resources.

　　Rural revitalization provides a new path for promoting fairness and efficiency. China has entered a highly cooperative society. Improving the skills of rural labor force through skills training will effectively improve the cooperation efficiency of the whole society. At the same time, rural revitalization will improve the quality and fairness of rural education, help solve the intergenerational transmission problem of poverty in the long run, and save human capital for economic development.

　　Rural revitalization provides a new guarantee for achieving common prosperity. Rural revitalization puts more emphasis on improving the availability of rural resources and the accumulation level of farmers’ human capital in the process of development, building the sustainable development capacity of rural areas in an all-round way, improving the income-increasing capacity of rural residents, narrowing the gap between urban and rural areas and consolidating the foundation of common prosperity, thus providing effective means for achieving common prosperity.

　　In view of the fact that rural industries and infrastructure are relatively weak, and the utilization rate of natural resources, human capital and other factors and labor productivity need to be further improved, in the process of comprehensively promoting rural revitalization, we should focus on accelerating rural infrastructure construction, fully tapping the advantages of natural resources in rural areas and accelerating the accumulation of human capital.

　　Accelerate infrastructure construction and promote high-quality development of agriculture.

　　From the perspective of improving supply quality, with the continuous improvement of China’s rural infrastructure, especially productive supporting facilities, the ability of rural areas to undertake industrial gradient transfer is increasingly enhanced, which not only plays an important role in promoting agricultural and rural technological progress and production mode innovation, but also plays a positive role in optimizing China’s industrial regional layout and smoothing the economic cycle in urban and rural areas. From the perspective of effectively expanding domestic demand, rural revitalization can further play the key role of investment in rural infrastructure and public services in optimizing the supply structure, continuously improve the income level and income-increasing ability of rural residents, release the huge potential demand in rural areas, and promote the expansion and upgrading of rural consumer markets.

　　To strengthen rural infrastructure construction, the key is to make great efforts to build a "new agricultural infrastructure", change the traditional mode of farmers’ "depending on the weather" and promote the transformation and upgrading of agricultural production methods. In practice, it is necessary to strengthen the following basic links: First, continuously standardize the high-standard agricultural production process, speed up the construction of standardized facilities such as greenhouses, and enhance the natural risk prevention ability of crops; Second, according to the regional characteristics and product characteristics, strengthen the construction of agricultural products storage and preservation, cold chain transportation and logistics facilities, extend the sales time or wrong season sales, and realize the preservation and appreciation of products; The third is to speed up the improvement of the rural logistics system at the county, township and village levels, build strong logistics facilities and digital infrastructure, make full use of new marketing methods such as e-commerce platforms and webcasts, and promote the effective matching of high-quality agricultural products with market demand; The fourth is to promote the innovative application of supply chain, carry out the construction of agricultural products supply chain with agricultural and commercial interconnection, and establish orderly and stable links with important regions or national logistics centers; The fifth is to establish and promote the standardization system and product quality certification standard system of agricultural products, build agricultural products brands, surpass the agricultural products standards in first-tier cities such as Beijing, Guangzhou and Guangzhou, strive for internationally accepted agricultural products certification, and enhance the global competitiveness of products.

　　Tap the advantages of natural resources and promote rural green development.

　　China’s rural areas have vast natural resources such as land and forest land, and the rich green ecological resources in rural areas have the advantage of being late-comer in the construction of ecological civilization.

　　To tap the advantages of natural resources in rural areas, we must first actively promote capital and new technologies to the countryside. On the one hand, support and encourage capital to go to the countryside to improve the utilization rate of rural production factors; On the other hand, actively promote the diffusion and application of new technologies and new products to rural areas, including the continuous improvement of agricultural mechanization and automation technology, and the wide application of new agricultural green technologies and digital technologies in agriculture and rural areas, so as to improve the productivity of rural production factors, thus promoting the transformation of rural production methods and farmers’ lifestyles, realizing the coordinated development of economic growth, farmers’ income increase and carbon emission reduction through clean energy supply and green industrial development, and opening up an effective path for green development in rural areas.

　　Secondly, continuously improve the "realization" ability of ecological capital. In the period of accelerating industrialization, the natural environment used to be an important factor restricting regional development, resulting in the so-called "green poverty" phenomenon of guarding Jinshan Yinshan without food. With the development of economy and society, people’s demand for green environment and ecological products continues to increase, and the economic and social value of green resources continues to increase. It is necessary to activate the sleeping natural resources, overcome the problem of "green water and green mountains are priceless", innovate the green financial service path, explore a new green development path with quantifiable and realizable value of ecological products, and truly transform the green water and green mountains into Jinshan Yinshan with increased income and wealth.

　　Finally, continuously improve the rural production, living and ecological environment. Develop ecological agriculture according to local conditions, implement green production projects, promote the deep integration of agriculture with tourism, education, sports, culture and other industries, and form a complex of nature+production+leisure+recreation; Invest more resource elements and public services in rural areas, strengthen the supporting construction of fire water supply, fire facilities and equipment, and small parking lots, improve water, electricity, communication and network facilities, and improve the modern livable level in the green ecological environment; Focusing on the treatment of rural garbage and sewage and the improvement of village appearance, we will promote the treatment of outstanding problems in rural human settlements in an orderly manner; Strictly observe the "red line" of ecological environment, and make scientific planning and rational development of tourism ecological resources.

　　Accelerate the accumulation of human capital and enhance the endogenous development ability of farmers

　　It is found that human capital is the lasting driving force of economic growth, and the differences of economic growth among countries mainly come from the differences of human capital accumulation and comparative advantages. To promote rural revitalization in an all-round way, we must focus on accelerating the accumulation of rural human capital. Strengthening the accumulation of rural human capital not only focuses on the long term, but also grasps the present. In the long run, in the overall situation of rural revitalization, we should pay more attention to improving the quality of rural education and the balance of resources, focus on blocking the intergenerational transmission of poverty after poverty alleviation, provide living water for rural revitalization of human capital accumulation, continuously improve the sustainable development capacity of rural areas and the income-increasing capacity of rural residents, accelerate the narrowing of the gap between urban and rural areas, and consolidate the foundation of common prosperity. To grasp the present, we should focus on three aspects:

　　First, in the process of rural revitalization, the improvement of agricultural and rural modernization will create more high-quality employment and entrepreneurial opportunities. We should improve the incentive policies, optimize the employment and entrepreneurial environment, attract more rural talents to return, create a large number of "Nong Erdai" successors of family agricultural management, rural cooperatives and leading enterprises, and promote the transformation of rural youth from identity identification to professional identity.

　　Second, in the process of promoting rural revitalization, we should pay attention to cultivating rural practical talent leaders who can lead one party and drive one, and expand the new generation of rural entrepreneurs, e-commerce talents and rural craftsmen in agricultural practice, so that rural human capital can reshape the new kinetic energy of rural development in combination with new technologies, new industries and new models.

　　Third, in the process of promoting rural revitalization, we should promote the transformation of farmers from farming to agricultural workers and local scientists. Through the training of labor skills and knowledge, guide farmers to change their identities from traditional farmers and migrant workers to modern agricultural workers and new agricultural management subjects; Through advanced agricultural means of production, agricultural machinery and equipment use training and technical service training, farmers will be promoted to improve their comprehensive quality of scientific and technological knowledge, management experience and technical skills, and become modern farmers who can effectively master new agricultural technologies, new machinery and new agronomy; By increasing the special financial investment in grass-roots scientific research, we will stimulate the innovation vitality of young agricultural science and technology workers, vigorously cultivate local scientists, and help more farmers change from knowledge users to knowledge creators.

1905 movie network news At present, the domestic online drama market is unprecedentedly prosperous, and some high-quality online dramas even surpass TV dramas in terms of click volume, broadcast volume and word of mouth, and there are countless stars who are popular or re-popular because of online dramas, such as Crystal and Peter in go princess go, Zray and Raquel in Remaining Crime, Pan Yueming in One Hundred Nights, and Hu Yi Tian and Shen Yuemei in To Our Simple Beauty are classic representatives.

　

Crystal Peter’s "go princess go" became popular overnight.

Go princess go can be described as the originator of online drama. Without any star support, the drama quickly attracted the attention of the whole network since its launch, with a maximum broadcast volume of over 200 million per day. Up to now, the cumulative broadcast volume has exceeded 4.24 billion, and the score of Douban score of 7.2 has broken many records. As a result, Crystal and Peter, the leading actors of the drama, became popular in the film and television circles overnight.

　

Zray Raquel’s "The Remaining Crime" exploded overnight.

After the Princess became popular, the second popular online drama was Yu Sin. As the first super online drama that broke 3 billion yuan before it was finished, it submitted a perfect ending report card with an excellent reputation of 8.2 points. Zray, the leading actor of the drama, became popular again and was promoted to a first-line niche, and Raquel, another leading actor, became the spokesperson of "eldest sister-in-law" in the eyes of the public overnight.

　

Pan Yueming turned red again.

As a typical figure who turned red again, there was Pan Yueming who relied on "Super Online Drama" and "White Night Chasing Murder". In this play, Pan Yueming played two roles and performed a pair of twins with different personalities very well. With Douban 9.0, up to now, the outstanding performance of breaking 5.38 billion yuan has turned red again, which not only won unanimous recognition in acting reputation, but also made overwhelming headlines.

　

Hu Yi Tian and Shen Yue’s "To Our Simple Little Beauty" attracted much attention.

In addition, last year, another online drama won the popularity of two unknown newcomers, Hu Yi Tian and Shen Yue, who became the new male gods and goddesses attracting worldwide attention by virtue of "To Our Simple Beauty". Up to now, the cumulative broadcast volume of the drama has exceeded 3.41 billion, and the Douban score is 7.2. Statistics show that the number of Weibo fans in Hu Yi Tian has increased from 710,000 to 6.6 million during the broadcast of the drama, which is amazing.

First of all, let’s take a look at the appearance of this whole car according to the routine. In terms of the appearance of the whole vehicle, the Range Rover Sport Edition adopts the family-style shape of Land Rover, and the middle net is very three-dimensional, with slender headlights on both sides, and the internal light groups are patchy, which is bright when lit. Judging from the waistline on the side of the car body, the new car is still a strong appearance, and the tradition of wide C-pillar can be continued, and the visual effect is acceptable. In the rear part, the Range Rover Sport Edition adopts many popular design elements, and the details of the rear taillights have become more fashionable after being redrawn.

In the interior, the Range Rover Sport Edition is still a traditional family style, and the whole design looks noble. The steering wheel is made of leather, which feels good and is equipped with shift paddles, which is very fun to drive. In the central control area, there are door handles, etc., which are covered and wrapped with a large amount of plastic and leather materials, and feel scientific and technological. It is equipped with a 10.2-inch central control LCD screen with clear display and relatively young design. The front row is also equipped with a dual-temperature automatic air conditioning control system to freely debug the most comfortable space atmosphere. Range Rover Sport Edition is equipped with leather seats.

Range Rover Sport Edition has a car length of 4970mm, a body width of 2047mm and a wheelbase of 2998mm, which is quite satisfactory. In the same class, the wheelbase of Range Rover Sport Edition ranks 43rd. This size exceeds most models in its class. The actual interior space performance is also very good. From the actual ride experience, the front and rear rows are relatively spacious. The design of skylight also increases the subjective space feeling of front and rear passengers. Among the models of the same price and class, the trunk volume of Range Rover Sport Edition ranks 7th. The space is relatively regular, without obvious protrusions, and the overall loading capacity is good.

The Range Rover Sport Edition is equipped with a 4.4 engine with a maximum output of 467kW and a maximum torque of 750Nm. It will definitely bring unforgettable control charm. The official measured acceleration of Range Rover Sport Edition is 3.8S, ranking 70th among SUV models with more than 800,000.

The active/passive safety configuration of Range Rover Sport Edition is complete, includingAutomatic parking、Zero tire pressure endurance tire、Automatic parking、Steep slope descent、hill start assist control、knee airbag、HUD head-up display、Anti-lock braking (ABS)、Braking force distribution (EBD/CBC, etc.)、Brake assist (EBA/BAS, etc.)、Traction control (ASR/TCS, etc.)、Active noise reduction、Engine start and stop、Side safety air curtain、Wireless charging of mobile phone、night vision system、LED daytime running lights、Forward reversing radar、Tire pressure monitoring、Steering wheel heating、Body stability control (ESP/DSC, etc.)、Rear reversing radar、Fatigue reminder、Remote parking、Child seat interface、Lane keeping (LKAS)Equal configuration.

Among them,Automatic parkingYou can avoid stepping on the brakes for a long time or needing to pull frequently;Steep slope descentCan safely pass through steep slope road conditions at low speed;knee airbagReduce the injury of the car interior to the occupant’s knees in the secondary collision.

If the above data and entries can’t fully understand the Range Rover Sport Edition, then we can give you a more comprehensive reference based on the word-of-mouth information of users who have purchased the Range Rover Sport Edition in history. It can be seen that what everyone is most satisfied with the Range Rover Sport Edition is its beautiful front face, and the big back row and high face value are also the points that everyone likes it.

A few days ago, Changan Mazda’s new car planning was exposed online. It is understood that this year Changan Mazda will launch BEV+REEV (pure electric+extended range) new energy vehicles to enter the domestic new energy market; After 2024, new products will be put on the market every year, so as to reverse the slow launch of new models in the market for many years.

Judging from the pictures exposed on the Internet, Changan Mazda will launch two new models with code names J90A and J90A-REEV in 2024; In 2025, two new cars codenamed J90K and J90K-REEV will be launched; NEW SUV and NEW CAR will be launched in 2026.

As one of the Japanese automakers, unlike Toyota and Honda, Mazda, which is positioned as a niche, does not have a high presence in China, especially since FAW Mazda announced its withdrawal. Mazda mainly relies on Changan Mazda as a car company in China.

Official website shows that at present, Changan Mazda’s models on sale include CX-8, CX-5, CX-4, CX-30, CX-50, Artaxella and Artaxella. Although Changan Mazda’s products are not few, most of them are actually discontinued, including CX-4 and Artaxella, and only one model has a good sales performance.

Retail data show that the cumulative sales volume of Changan Mazda in 2023 was 88,564 vehicles, compared with 92,748 vehicles in 2022. Among the sub-models, the model with the highest sales volume is Angkor Sela, with 49,419 vehicles, accounting for 55.80% of the total sales volume; CX-5 and CX-50 lines followed, with sales of 17,884 vehicles and 10,265 vehicles respectively. The performance of other models is very general, such as CX-4′ s annual sales of 3908 vehicles; Artz is3,438 vehicles; The CX-30 is2,685 vehicles; There are 185 CX-30 EV.

However, despite its poor performance in China, Changan Mazda still does not intend to give up this market, but will vigorously lay out this market. In April last year, Mazda China announced the transformation strategy and vision of the electrification era and established a brand-new cooperation model with Changan Automobile. According to the plan, Mazda’s transformation strategy in the era of electrification is divided into three steps: from 2022 to 2024, it will strengthen the development for the era of electrification; In 2025-2027, we will strengthen the development of battery technology and take the lead in putting pure electric vehicles into the China market; From 2028 to 2030, pure electric vehicles will be officially introduced, and the transition will be made to the era of electrification.

In July of the same year, Masahiro Moro, CEO of Mazda, said in an interview that due to the fierce competition in China’s electric vehicle market, Mazda’s business in China may be difficult, and its strategy in China needs to be thoroughly reformed. Mao Longsheng said that Mazda’s operation in the world’s largest automobile market will become more and more difficult in the next year to 18 months. The output is low, but the profit pressure is increasing.

However, as far as the current market is concerned, Changan Mazda is still in a very passive situation. It is extremely difficult to achieve sales growth only by relying on a model of Angkor Sela, which also means that Changan Mazda urgently needs an explosive model to save sales.

Sumioka Takashi, president of Changan Mazda Automobile Co., Ltd., previously said: "China is Mazda’s most important overseas market, and Mazda will continue to deepen its cultivation." From the analysis of the exposed new car planning, Changan Mazda will make efforts in the new energy market, which may be a better choice for Changan Mazda, which has a low sales volume of fuel vehicles, to adapt to market development and realize electrification transformation.

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　　[Special correspondent of Global Times in Germany Aoki Special correspondent of Global Times Zhen Xiang] On the 9th, US President Biden will leave for Europe to visit Britain, Belgium and Switzerland to attend the Group of Seven (G7) summit, NATO summit, US-Europe summit and US-Russia summit. China and Russia will be the key topics of Biden’s trip to Europe, according to statements made by senior NATO and EU officials on the 8th. Biden hopes to use his first foreign visit since he was elected president of the United States to prove to his allies that "the United States is back." However, many western media and experts believe that the relationship between the United States and Europe can not go back to the past.

　　China and Russia will be the key topics of the G7 and NATO summits.

　　According to the "Deutsche Welle" report, Biden met with visiting NATO Secretary General Stoltenberg at the White House on the 7th. The two agreed that it is essential to strengthen transatlantic relations in today’s increasingly fierce global competition. They also discussed the possibility of strengthening NATO’s strength to meet new challenges. These challenges include global terrorism, climate change and tensions with China and the Russian Federation. Stoltenberg said that he agreed with Biden’s two-track strategy toward Russia, including "deterrence, defense and dialogue". The senior NATO official said that cooperation with China can bring economic opportunities to the West, but some problems also make it difficult for NATO to develop relations with China. According to the US political news network, Stoltenberg stressed that NATO should turn its focus to China, and the joint statement issued by the NATO summit will involve more China.

　　European Council President Michelle hailed "America is back" on Monday. According to Reuters’s report on the 8th, Michelle said that Biden’s trip to Europe this week marked that multilateralism "survived" after the Trump administration, which means that the EU has a very strong partner to promote the multilateral model. He predicted that the G7 Summit would discuss the need for the West to take a more active approach to defend its values in the face of "China’s rise and Russian self-confidence".

　　"The United States and Europe can’t go back to the past."

　　The 78-year-old Biden will have the most intense itinerary since he took office. After their departure on the 9th, he and his wife will first arrive at Milden Hole Air Force Base in the UK, where they will meet with the US Air Force stationed in the UK. On the 10th, they will visit Cornwall, England, where Biden will meet with British Prime Minister Johnson and reiterate the special relationship between the United States and Britain. From 11th to 13th, the American president will attend the G7 summit, then fly to Brussels to attend the NATO summit on 15th and have a private meeting with Turkish President Erdogan. On the 16th, Biden will travel to Switzerland to meet with Russian President Vladimir Putin.

　　Agence France-Presse said on the 8th that Biden’s current visit will "guard democracy" and "hold high the banner" for western countries at a "turning point". Biden wrote in the Washington post a few days ago that the "democratic alliances and institutions" that played a great role in the last century have the ability to deal with the current threats and opponents, and this week will prove this.

　　"Biden will be warmly welcomed." According to the Associated Press reported on the 8th, when Biden arrives in Europe, he will find that all the hosts welcome him. For most American allies, Biden gave them a sigh of relief. Former US President Trump often creates chaos, accusing NATO of relying on the United States and insulting the EU. In contrast, Biden emphasized his support for international diplomacy. However, European countries are also wary of the United States. Trump has left them with an indelible shadow, and there are many differences between the United States and Europe. For example, although Biden has begun to rebuild relations with NATO, Washington still hopes that other NATO members will increase their defense spending, which is Trump’s previous position.

　　"The United States and Europe can’t go back to the past." Germany’s "Focus" magazine commented on the 8 th that Biden hopes to open a new transatlantic relationship, but the United States has changed and Europe also hopes to gain more "strategic autonomy." Europe is worried that there will be a Trump-style president in the United States again, and the relationship between the United States and Europe will once again be cracked. Europe hopes to strengthen cooperation with the United States in key areas such as climate, vaccines, trade and security, but it will also have its own policies on relations with China and Russia. According to Washington post, experts believe that Biden has not appointed the permanent representative of the United States to NATO and the ambassador to the European Union, which shows that Washington is indifferent to this matter. European commentators also realize that no matter how friendly Biden is in London and Brussels, the United States increasingly regards Europe as a secondary partner in its increasingly fierce competition with China.

　　Will the US-Russia summit go smoothly?

　　The US-Russia summit will be the highlight of Biden’s trip to Europe. Many people in the United States believe that Biden should not meet with Russian President Vladimir Putin and that this meeting is a "reward" for Moscow. According to Bloomberg News, US Presidential National Security Assistant Sullivan said on Monday that holding a summit meeting is the best way for the United States to clarify the intentions of the Russian government. The summit will give Biden the opportunity to show Putin the intentions and capabilities of the United States and Putin the intentions and capabilities of Russia. He also believes that Biden’s "participation in this meeting will be smooth."

　　However, Sullivan also lowered people’s expectations of the summit results on Monday. "If you have to wait for really important results, you may have to wait for a long time, which is conceivable." On the 8th, Agence France-Presse listed five key issues that will be involved in the US-Russia summit, including election intervention, arms control and diplomatic tensions, and believed that both sides complained about each other on these issues. Before the summit, politicians of both the United States and Russia expressed pessimism about the outcome of the summit.　 　 　 　 　

　　According to media reports such as the US "Axios" news network, Biden spoke with Ukrainian President Zelensky on Monday and invited him to visit the White House this summer. Zelensky had hoped to meet Biden before the US-Russia summit, but this request was rejected by Washington. As the US-Russia summit approaches, Ukraine keeps putting pressure on NATO and the United States, hoping that Kiev can join NATO as soon as possible. Stephanie Hina, Ukraine’s deputy prime minister in charge of European and Euro-Atlantic integration, said that it was NATO’s "biggest mistake" for western countries to remain silent on Ukraine’s accession to NATO, and Kiev had been expecting a "historic response" since the NATO summit in Bucharest in 2008.

BYD owns Dynasty series and Ocean series, and Ocean Net models include pure electric marine life series and warship series represented by DM-I. Seals are one of the representative models of BYD Ocean series, which is similar to Han EV/DM of Dynasty series, but compared with Han, seals have a more fashionable style and are more interesting in performance.

From the appearance, there are essential differences between seals and Dynasty series. We will think that the models of Dynasty series are more traditional and conservative. The design of seals refers to Ocean-X, which caters to young consumers and gives people a feeling similar to Porsche Taycan in coupe.

Let’s look at the highlights of the appearance and interior. The body size meets the standard of a medium-sized car. The length, width and height parameters are: 4800/1875/1460mm, but it is still smaller than Han in size. The whole car uses a coupe shape, and the advantages of battery arrangement can ensure more comfortable riding in the back row. From the side of the car body, the waistline of the whole car is strong and strong, and the rear bumper echoes the front face, which has a good sense of movement.

The interior part further strengthens the design elements of "marine aesthetics", with a 15.6-inch central control large screen supporting adaptive rotation function and a 10.25-inch full LCD instrument panel, which is much more atmospheric than dolphins. In the configuration, there are front and rear collision warning, L2 driver assistance system, mobile APP remote control, etc. Among them, L2 assistance system uses 3 millimeter wave radars /6 ultrasonic radars and 5 cameras. In terms of configuration, I think it is better than Han EV, and the technology is more advanced. If you want to buy a bigger space, Han EV is better.

Let’s take a look at the technical highlights used by seals: CTB battery body integrated design, E 3.0 pure electric platform, heat pump air conditioning and so on. CTB technology is also the structural composition of the battery. The battery pack of the electric vehicle is composed of a plurality of battery cells, which are combined in series. CTB technology integrates the upper shell of the battery with the floor of the vehicle to become a structural part of the chassis. The battery and the tray are installed in turn, which can improve the body rigidity and reduce the weight, reaching the body rigidity level of 40,500 N m/.

CTB technology means a higher safety factor, which can not only improve the integrity of the vehicle, but also reduce the center of gravity of the vehicle, realize the axle load distribution of 50:50 before and after the vehicle, and form a vehicle with obvious motion characteristics and wide interior space, such as Elk’s test speed of 83.5km/h and wheelbase of 2920 mm.

E 3.0 pure electric platform integrates motor controller MCU, high-voltage distribution box, DC-DC and on-board charger, etc., which is more integrated. For example, the motor sensor detects the operation of the motor, distributes the power of the wheels, achieves the balance of the car body, and improves the comfort of riding. However, the maximum horsepower of the rear-drive version of the motor is 204 horsepower, which is the same as that used in more than 100 thousand cars.

The heat pump air conditioner with wide temperature range and high efficiency has better heating effect than the traditional PTC, such as faster heating and wider temperature control. PTC system uses power battery for power supply, and the ratio of required energy to battery energy is 1; 1, for example, the battery capacity is 80AH, the output voltage is 320V, the PTC power is 2KW, and the heat pump air conditioner can generate 1KW.H of heating power, so that the cruising range can be increased by 10-20%.

The price of Seals is 2098-286,800 yuan, which is matched with Ferrous lithium phosphate lithium-ion batteries. The battery voltage is 750V, and the corresponding CLTC mileage is 550km, 700KM and 650KM, which is similar to the 715KM and 610KM of the 2022 Han EV. The total motor power is 150KW and 230KW.

From the perspective of cost performance, the CLTC model with a mileage of 700KM with a price of 259,800 yuan is the most worth buying, but if you add 10,000 yuan, you can buy Han’s second-lowest model, so it is better to buy Han. However, you can also consider a 550KM high-profile model. These configurations such as Dana speakers, seat heating and ambient lights are enough for home use and transportation.

To sum up, at the price of more than 200,000 yuan, many of us used to consider B-class cars or compact cars with high configuration, but the popularity of BYD Han shows that everyone trusts the pure electric vehicles with long cruising range under BYD brand, and will also consider the pure electric vehicles at this price. Besides Han, the price performance ratio of Seal is also good. What do you think?