The 10th Anniversary Special Issue of Cells

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2021 is Cells The tenth anniversary of the publication of periodicals. As of now,Cells The journal has published more than 9,300 papers, and its homepage has been visited by more than 50,000 people every month. We support you. Cells The authors, readers, peer reviewers, editors and others who have contributed to the journal express their sincere thanks.

To celebrate this important moment, the journal created a series of commemorative special issues "10th Anniversary of Cells— Advances in Cell Microenvironment ",this special issue invited Professor Alexander Dityatev, Professor Mark R. Wilson and Professor Dmitri Rusakov, experts in the field of cell microenvironment, as guest editors. Related research topics focused on include, but are not limited to: ECM remodeling, mechanical transduction, stem cell niche, tumor microenvironment, neural network and synaptic microenvironment, reconstruction and repair of cell microenvironment with injectable ECM scaffold, gene therapy and pharmacological targeting, experimental modeling of microenvironment using micro-mode and micro-fluid, and system biology of cell microenvironment. We sincerely welcome all scholars and researchers in this field to contribute enthusiastically.

Deadline for submission of special issue: September 15th, 2022.

Guest editor

Prof. Dr. Alexander Dityatev

German Centre for Neurodegenerative Diseases (DZNE)

Prof. Dr. Alexander Dityatev is a professor at the German Center for Neurodegenerative Diseases (DZNE) and the head of the molecular neuroplasticity group. He received his doctorate from the Institute of Evolutionary Physiology and Biochemistry in St. Petersburg, Russia. His research group mainly studies extracellular matrix (ECM), and its potential mechanism involves many mechanisms, including L-type voltage-gated Ca2+ channels, NMDA receptors, Ca2+-dependent K+ channels and the regulation of axonal excitability, focusing on the mechanism of controlling ECM up-regulation and downstream events affecting synaptic and cognitive functions. So far, his article has been cited 8570 times.

Prof. Dr. Mark R. Wilson

University of Wollongong, Australia

Prof. Dr. Mark R. Wilson is a senior professor of chemistry and molecular biology at the University of Wollongong, Australia. He took the lead in identifying and studying extracellular (secretory) mammalian chaperones and their roles in protein’s homeostasis (protein homeostasis). He also conducted basic research on protein homeostasis mechanism of supporting diseases, such as motor neuron diseases. His research team has accumulated expertise in a wide range of technical fields, including confocal microscopy, flow cytometry and the production of recombinant proteins that require a lot of post-translational modifications (such as extracellular chaperones). So far, his article has been cited 6562 times.

Prof. Dr. Dmitri Rusakov

university college london

Prof. Dr. Dmitri Rusakov is a professor at University College London and a member of the synaptic imaging team. He mainly studies the formation and integration of signals in neural circuits of astrocytes, the organizing principles of synaptic structure and function, the activity-dependent control of neurotransmitter release, and the nano-molar landscape of basic Ca2+ in neurons and astrocytes. Its research is helpful for interdisciplinary efforts to solve the cellular mechanism of epilepsy and other neurodegenerative diseases. Up to now, his articles have been cited 8141 times.

Special issue details page:

https://www.mdpi.com/journal/cells/special_issues/Anniversary_Cell_Microenvironment

CellsPeriodical introduction

Editor in chief:

Cord Brakebusch, The University of Copenhagen, Denmark

Alexander E. Kalyuzhny, Neuroscience, USA

It mainly publishes research in cell biology, molecular biology and biophysics. At present, it has been included in databases such as SCIE (Web of Science), PubMed, MEDLINE and PMC.

2020 Impact Factor: 6.600

2020 CiteScore: 6.663

Time to First Decision: 16 Days

Time to Publication: 39 Days

 
 
 
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Cancer is divided into poor cancer and rich cancer.

  A recent study published in Cancer magazine found that there is an important correlation between socio-economic status and cancer types. Rich and poor people are prone to different types of cancer.

  For those who are frightened by the news such as "Julie cuts twice every three years" and "Liver cancer can be inherited", please note that this discovery shows that cancer is the result of the interaction between genetic factors and environmental factors in a long process, just like an egg can’t become a chicken without proper temperature, it is mainly environmental factors. Even if you are related to cancer patients, as long as you pay attention to prevention, it is still possible to shut cancer out!

  Interview expert: Professor Qin Shukui, vice president of Bayi Hospital and director of the Cancer Center of the whole army.

  1 Carcinogenic environment leads to the distinction between "rich cancer" and "poor cancer"

  A recent study published in Cancer magazine found that cancer can be divided into "rich cancer" and "poor cancer".

  In this study, researchers followed up 3 million cancer cases diagnosed in the United States from 2005 to 2009, covering 42% of the population in the United States and covering the richest and poorest communities in the United States.

  The results show that there is an important correlation between socio-economic status and cancer types. Richer people are more likely to suffer from melanoma, thyroid cancer, skin cancer and testicular cancer; The poorer people are more likely to suffer from Kaposi sarcoma, laryngeal cancer, cervical cancer, penile cancer and liver cancer.

  Why is this so?

  The reason is that the causes of cancer (environment and living habits) are different, and eventually different types of cancer will be produced.

  Cancer is the result of the interaction of heredity and environment.

  Case: There is a family. The eldest son was admitted to the university and went to other places, and then he stayed to work in other places, while the youngest son stayed with his mother all the time. Later, the mother died of cancer, and then, the youngest son died of cancer.

  This case shows that there are genetic defects in cancer families, but "common living environment and way" may play an important role.

  Case: Ms. Leah in Britain divorced her husband because of rectal cancer. She believes that her husband likes red meat, drinks and spicy food, and has a bad temper, insists on smoking and is getting obese year by year. This lifestyle will affect her and her children, and she wants to get rid of this living environment.

  There is an article in the British Medical Journal detailing "marital diseases", saying that if one of the spouses is sick, the prevalence rate of the other will increase a lot, from cancer, diabetes, hypertension to ischemic heart disease. The reason is that people who live together for a long time have many diseases at the same time because of the same eating habits and similar lifestyles.

  Modern genetics shows that cancer depends not only on genetic factors, but also on "being affected by acquired carcinogens and cancer promoters". Breast cancer, lung cancer, liver cancer, esophageal cancer, cervical cancer and colorectal cancer are greatly influenced by bad living habits and environmental factors.

  China also has "poor cancer" and "rich cancer"

  Case: The 31-year-old "True Water Without Fragrance" (net name) has been feeling intense nausea for more than a month. She usually pays great attention to maintaining her health. She eats miscellaneous grains for breakfast every day, drinks tea and doesn’t touch alcohol and tobacco. She has regular physical examination every year and has never had any major problems. This time, she thought vomiting was a sign of pregnancy, but after a check, the result was: advanced rectal cancer!

  "True water has no fragrance" slowly pieced together the clues of his illness: although he sometimes eats miscellaneous grains, he eats a lot of meat, and he rarely exercises. He is 155 cm tall but 128 kg fat. At this time, her mother told her that her grandmother died of esophageal cancer, her grandfather died of lung cancer, and an uncle also had rectal cancer!

  Her grandmother’s esophageal cancer belongs to "poor cancer" and her rectal cancer belongs to "rich cancer".

  What are the poor and rich cancers in China?

  "Poor cancer" also includes liver cancer, stomach cancer, esophageal cancer and cervical cancer. "Cancer-rich" also includes lung cancer, colorectal cancer, breast cancer, lymphoma and prostate cancer.

  4 "poor cancer" is related to long-term chronic infection.

  Why do liver cancer, gastric cancer, esophageal cancer and cervical cancer belong to "poor cancer"?

  A study in the Annals of Oncology shows that some cancers can be caused by long-term chronic infection. In China, hepatitis B virus, Helicobacter pylori, human papillomavirus (HPV) and EB virus are the most common infectious and carcinogenic factors.

  Infected with hepatitis B virus, it further evolves into cirrhosis through acute and chronic inflammation, and a small number of patients can eventually lead to liver cancer.

  Helicobacter pylori is the most common infectious bacteria, which may cause gastritis and peptic ulcer, and long-term infection may promote gastric cancer.

  The bane of cervical cancer and its precancerous lesions has been proved to be human papillomavirus infection.

  The high incidence of nasopharyngeal carcinoma is closely related to EB virus infection.

  Generally speaking, these cancers related to long-term chronic infection mostly occur in economically underdeveloped areas, where the natural environment is often bad, the nutritional conditions are poor, the hygiene level is low, and the living habits are not good. Therefore, these cancers are easy to develop.

  5 "cancer-rich" is related to modern lifestyle.

  Why are lung cancer, colorectal cancer, breast cancer, lymphoma and prostate cancer called "rich cancers"?

  Rectal cancer with "true water without fragrance" is regarded as a typical "cancer-rich". In terms of pathogenesis, colorectal cancer is influenced by related genes, such as diabetes, hypertension and coronary heart disease. Lifestyle, perennial high-fat diet, lack of dietary fiber intake, sedentary inactivity, untimely defecation or habitual constipation are all common causes.

  Why excessive intake of high-fat food is one of the carcinogenic factors?

  A new study found that a high-fat diet can change the intestinal microecology (that is, microbial composition)-some bacteria increase, while others decrease. As a result, the immune defense against intestinal cancer is reduced, and the incidence of cancer is increased.

  Why sedentary, more susceptible to cancer?

  The immune function in human body is enhanced with the increase of activity, and sedentary can make the human body lack enough immune cells.

  An epidemiologist in Canada found that in the United States, 49,000 cases of breast cancer and 43,000 cases of colon cancer are associated with inactivity every year, and breast cancer and colon cancer seem to be two cancers closely related to exercise.

  Blocking infection can effectively prevent "poor cancer"

  6 How to prevent "poor cancer"?

  There is no direct causal relationship between infection and cancer, and it will not be "killed in one blow". Viruses and germs lurk quietly in our bodies, waiting for an opportunity to attack. This process takes about 10 years or more. If we can stop their spread and eliminate them in the cradle, we can effectively prevent the occurrence of cancer.

  First, get vaccinated. According to statistics, 95% of infants and children in a certain area were injected with hepatitis B vaccine in 1984. Twenty years later, the number of hepatitis B carriers dropped from 10% to 20% to 0.2%, and the incidence of liver cancer decreased by 70% to 80%.

  Second, early treatment. Helicobacter pylori can be completely eradicated by antibiotic combined therapy, which can not only relieve gastritis and gastric ulcer, but also play a good role in resisting the further development of gastric cancer.

  Third, do screening. Women over the age of 30 must have regular cervical screening. At the same time, protect yourself, pay attention to using condoms, don’t have sex too early and limit the number of partners.

  Finally, the dining system. Helicobacter pylori and other germs are highly contagious, and can be transmitted through hands, food and tableware. It is also best to implement a separate meal system in family life.

  Healthy lifestyle can prevent "cancer-rich"

  7 How to prevent "cancer-rich"?

  "Cancer-rich", such as colorectal cancer, breast cancer and lymphoma, has no unique and significant inducement, and some people think it is difficult to prevent it.

  However, this kind of rich disease also has some common causes-eating too much, eating a high-fat and high-protein diet, and lack of exercise.

  Therefore, the way to prevent it is to establish a healthy lifestyle. Compared with the "poor cancer" caused by chronic infection, it is more difficult to do and requires greater determination and perseverance! (Li Lanling)

FSD is about to enter China, can it add fire to domestic autonomous driving?

Among Tesla’s core technologies, FSD ("Full Self-Drive") is undoubtedly the most concerned core. However, due to various restrictions including laws and regulations, FSD has not been introduced into the domestic market, which has become a big regret for Tesla owners. However, it has recently been reported that the relevant person in charge of the Intelligent Manufacturing Promotion Department of the Shanghai Economic and Information Committee introduced that in the next stage, Shanghai will further deepen its cooperation with Tesla and promote the layout of functional sectors such as autonomous driving and robots in Shanghai. There are indications that the policy barriers for Tesla FSD to enter the domestic market are constantly being cleared. Chu Ruisong, general manager of Baidu Smart Car Division, even directly predicted that FSD will enter the China market this year or next year, and will be opened on a large scale in 2025.

1. Tesla needs FSD to re-establish its technological advantages.

From Tesla’s point of view, it is becoming more and more urgent to introduce FSD into the domestic market.

First of all, at present, domestic mainstream car companies are advancing by leaps and bounds in the field of smart electric vehicles, and Tesla’s technological advantages are rapidly approaching by domestic car companies. To this end, Tesla, which has a relatively limited vehicle matrix, can only sacrifice weapons with cost performance. Improve the cost performance of products through continuous price reduction, and then increase terminal sales. In this case, it is of great significance to introduce the latest FSD technology into China, which can help Tesla reconfirm its leading position in technology.

Secondly, Tesla’s FSD needs to accumulate a large number of actual road data to continuously optimize the algorithm. Therefore, after the introduction of FSD into China, Tesla can help Tesla collect a large number of valuable data and lay the most solid foundation for the iterative update of the algorithm after meeting the requirements of domestic laws and regulations on data collection.

Finally, Tesla is the standard-bearer of "Software Defined Car". FSD is expensive in North America, and the price of bicycles is nearly 100,000 RMB. And the gross profit margin of software is very high. Under the background of Tesla’s continuous price war, if FSD can contribute enough sales volume, it will give Tesla greater confidence to fight the price war.

2. Does FSD still have advantages?

As one of the labels of Elon Musk, Tesla has been investing a lot of money in FSD to maintain the advanced technology. Domestic car companies choose Tesla’s technical route more in many key technical choices to ensure that there will be no strategic mistakes in the direction.

In the whole automobile industry, Tesla was the first to apply the neural network model Transformer to the intelligent driving of mass production vehicles, about two years earlier than other automobile companies. Compared with the previous convolutional neural network CNN, the neural network model Transformer has been significantly improved in efficiency and accuracy, but it also requires more data. In 2022, Tesla was the first in the industry to release the Occupancy Network that can detect general obstacles. In addition, Tesla FSD’s solution is a set of solutions that do not rely on high-precision maps, which greatly expands the scenarios in which FSD can be applied.

For many domestic automatic driving/driving assistance schemes, although we can also realize the functions of automatic lane change, automatic overtaking and automatic on-off ramp, we are expanding from expressway to urban road scene. However, our scheme relies more on lidar and high-precision maps. Compared with Tesla’s pure vision scheme, the former is more expensive and the data fusion is more difficult. Moreover, most domestic autonomous driving technical solutions rely on high-precision maps, so there are many limitations in the use of scenarios. Therefore, these factors are integrated, and Tesla FSD still has its index significance.

However, we also have to admit that although FSD has no small lead, it still faces many challenges to fully realize FSD in domestic road conditions. On the one hand, domestic legislation needs to keep up with it in time, giving a green light at the policy level for enterprises to deploy FSD; On the other hand, the domestic working conditions are more complicated, especially on urban roads, there will be many unpredictable long tail working conditions. In this case, in a short period of time, it is basically difficult for L4-level autopilot to be deployed commercially. Even if the performance of FSD is advanced, it can’t escape this category. Therefore, how Tesla chooses the deployment scope of FSD and maximizes the performance advantages of FSD is a big test for Tesla.

3. Will the China autonomous driving market "wolf come"?

For domestic car companies, there is a phenomenon worthy of attention. At present, not only Tesla’s FSD, but also Mercedes-Benz’s Drive Pilot are actively getting approval from China government departments to introduce relevant technologies into the domestic market. Especially the Drive Pilot of Mercedes-Benz, although there are many restrictions, it is the only L3-level automatic driving system in the world that allows drivers to engage in other activities in the car without paying attention to the operation of the whole vehicle. At present, no vehicle manufacturer in China can give such a promise to Mercedes-Benz.

As the world’s largest smart electric vehicle market, it is a general trend for foreign car companies to introduce intelligent networking technology including the most advanced autonomous driving technology to China as soon as possible. If they don’t do this, they will be widened by independent brands in China. The brand appeal accumulated in the past will also completely disappear. At the same time, considering that autonomous driving is a technology that needs long-term accumulation, continuous optimization and is closely related to local conditions, it will be unstoppable for Tesla FSD and other foreign car companies to enter China in any dimension.

The introduction of Tesla has accelerated the reshuffle process of domestic electric vehicles and even the whole new energy vehicle market. However, it has also created the global group operational advantage of China brand new energy vehicles. A large number of China-branded cars have gone abroad, attacking cities in overseas markets. With Tesla’s introduction of FSD and Mercedes-Benz’s introduction of Drive Pilot into the domestic market, the competition in the whole market will become more intense, but it may also make the domestic autonomous driving technology leap to a new level. Only in this way, China brand cars will not only be able to stand at home, but also be expected to continue to "roll up" those multinational car groups that are not leading in technology in overseas markets, so as to gain a larger market share for China brand cars in the global auto market.

Cadillac car price list What are the prices of five Cadillac cars?

In the field of luxury cars, Cadillac attracts the attention of many consumers with its exquisite design and excellent performance. Next, let’s explore the price points of five Cadillac cars to meet your expectations of luxury cars.

  • Cadillac CT4This entry-level sports car shows Cadillac’s control of cost performance with its price of 239,700 to 259,700 yuan. Equipped with 2.0T engine and 8AT gearbox independently developed by GM, it brings surging power to drivers. Facing the challenge of luxury brand compact cars such as BMW 1 Series, Audi A3 and Mercedes-Benz A-Class, CT4 also competes with Toyota 86, Subaru BRZ and other sports cars with excellent sports performance.
  • CT5As a mid-level car of Cadillac, the price range of CT5 is 279,700 to 339,700 yuan. Although the appearance maintains the classic design, the configuration upgrade is its highlight. The new Apple wireless car play and Baidu car life, as well as the top 12-inch full-color customizable dashboard and Baidu intelligent voice interactive system, have improved the technological content of the driving experience.
  • XTSXTS, with a price range of 2999-359900, as a luxury business car of Cadillac, has been integrated into the design of ESCALA concept car, and its technology configuration has been significantly upgraded, including 12-inch full LCD dashboard and 4G+wifi hotspot. Entertainment interconnection is also realized through APP, which adds convenience to business travel.
  • ATS-LATS-L, ranging from 298,800 yuan to 428,800 yuan, continues Cadillac’s luxury and practicality, and the addition of car-Wi-Fi hotspot function makes the configuration more abundant and practical.
  • CT6The top-end CT6, the price range is 379,700 to 489,700 yuan. As a modified model, although the sports style is cancelled, new intelligent configurations such as Apple Wireless CarPlay and Baidu CarLife, as well as Baidu Intelligent Voice Interactive System, make it feel by going up one flight of stairs in luxury and technology.

Cadillac’s price strategy obviously focuses on the richness of configuration. The cost performance of the entry-level model CT4 is attractive, while CT6 is more suitable for users who pursue luxury experience. Each model meets the needs of different consumers with its unique advantages. If you are interested in Cadillac cars, this price information will help you make a purchase decision.

凯迪拉克CT4

Changan new energy electric vehicle Yidong ET accelerates 100 kilometers for 10 seconds!

Yidong ET is a pure electric vehicle with hatchback design. The car has been unveiled at the 2018 Guangdong Auto Show, and it is finally officially confirmed that it will be officially listed on May 11 this year. Yidong ET is based on the design of Changan classic hatchback Yidong XT. Vehicle size information: the length, width and height of the vehicle are//,and the wheelbase is.

Appearance, the car uses a closed air intake grille, which is the biggest appearance difference from the fuel version. This design can easily distinguish whether it is a new energy vehicle or not, with high recognition. In addition, Yidong ET also optimizes many details. Chrome plating is added to the triangular decoration under the lamp group, and the layering of lines is very obvious. Especially the very slender and harmonious sides and 17-inch wheels enhance the overall appearance of the vehicle. Quite a bit sporty.

In terms of interior, Yidong ET also maintains most of the same characteristics as Yidong XT. The cool version is equipped with a full LCD instrument panel and a 10-inch central control panel (the cool version is 7 inches), but don’t worry, cruise control and ESC body stability system are standard in all departments. In terms of configuration, the new car is equipped with Changan in-call 3.0 in-vehicle interconnection system, and also provides a series of safety configurations such as front airbag/front and rear integrated side air curtain/battery intelligent electric heating system. And tire pressure monitoring.

In terms of power, the new car is driven by pure electricity, equipped with a ternary lithium-ion battery pack with a capacity of 52.6kWh, with a maximum power of 100kW(136Ps) and a peak torque of 235 Nm. The top speed can reach 140 km/h. The gearbox is matched with a fixed speed ratio single-speed gearbox.

If the friends have any ideas, you can leave a message below to discuss.

The battery life is 700 kilometers! Changan Automobile Deep Blue SL03 is officially released

In the market, it launched an electric car with its sub-brand Deep Blue, which symbolically broke the conventional limit of battery life and reached a striking 700 kilometers.

The achievement of this mileage not only reflects its profound technological accumulation in the field, but also reflects its far-reaching consideration for future travel methods. The advent of Deep Blue SL03 is undoubtedly a great news for consumers who have long been concerned about the development and innovation of new energy.

It not only meets the needs of long-distance driving with its excellent battery life, but also stands out in the highly competitive market with its unique design and technical configuration. Changan Automobile’s move obviously sets the tone for the future trend of the automotive industry, that is, the integration of battery life, design and technology is the key to the development of new energy vehicles in the future.

The exterior design of the Deep Blue SL03 is a direct response to the aesthetic trend of contemporary young consumers. The sleek body lines, coupled with a slip-back roof, not only greatly enhance the vehicle’s dynamic aesthetics, but also virtually reduce air resistance, helping to achieve a longer range. The hidden door handles further highlight the futuristic feel and integrity of the vehicle, while the dive-style front design combined with the sharp headlights shape shows its extraordinary sporty genes.

These design details are not only the pursuit of modern design trends, but also the perfect combination of power performance and aesthetics. Changan Automobile proved to the market through the dark blue SL03 that technology and fashion can be perfectly integrated in the design of electric vehicles, providing consumers with a driving experience that is both environmentally friendly and extremely aesthetic.

Turning to the interior of the Deep Blue SL03, the interior of this sedan is equally striking, successfully combining a sense of luxury with a sense of technology to provide drivers and passengers with a comfortable experience that exceeds expectations. Soft-touch materials and high-grade leather are used extensively in the interior to create a warm and refined environment. The seat design not only emphasizes the principle, providing excellent support and comfort, but also reflects the fine polishing of details by Deep Blue.

The design concept of the central console is simple and clear, but it does not lose the technological style. It is equipped with a large-size touch screen and a digital LCD instrument panel, which significantly enhance the intelligence level of the vehicle. In addition, the addition of ambient lights and the configuration of the panoramic canopy undoubtedly enhance the emotional experience during driving, allowing people to enjoy a quiet and comfortable journey even at night.

The performance of the Deep Blue SL03 in terms of power performance is also commendable. The car is expected to be equipped with two different power output motors, each of which can peak at 225Nm, ensuring that the vehicle can be quickly accelerated whether in urban congestion or on open highways. The layout not only guarantees the stability of the acceleration process, but also allows the acceleration time of 100 kilometers to be only 4.9 seconds, demonstrating the outstanding performance of the Deep Blue SL03.

More importantly, the Deep Blue SL03 is also equipped with advanced intelligent driver assistance systems and a new generation of arrays, which not only greatly improve driving safety, but also make driving easier and more enjoyable. The intelligence system can monitor the environment around the vehicle in real time, and provide the driver with the most suitable driving suggestions through accurate data analytics to ensure that every trip is safe and worry-free.

The deep blue SL03’s battery life is impressive, providing two battery options, capable of achieving a range of 515 kilometers and 705 kilometers respectively, and the performance of its extended range version is even more amazing, with a comprehensive range of 1,200 kilometers. This battery life performance not only means that there is almost no need to worry about power problems in daily use in cities, but also can easily handle even long-distance travel, greatly broadening the use of electric vehicles and client base.

The deep blue SL03 proves to the market that new energy vehicles can fully meet the travel needs of modern people, whether it is short-distance or long-distance, it can provide stable and reliable power support.

In terms of intelligent experience, the Deep Blue SL03 has spared no effort to demonstrate the strength of its future technology. The intelligent driver assistance system on the vehicle integrates advanced algorithms and 34 sensors, including 4D millimeter wave radar and ultrasonic radar, which can fully perceive the surrounding environment of the vehicle and monitor possible safety hazards in real time, thus providing more accurate driving assistance and safety warnings.

The addition of these intelligence systems not only significantly improves driving safety, but also greatly reduces the driver’s driving burden, making the driving experience more relaxed and pleasant. In addition, the intelligence of Deep Blue SL03 is also reflected in its interaction with users, providing drivers with a more personalized and convenient driving and life experience through intelligent voice assistants and vehicle to everything services.

When it comes to safety, the Deep Blue SL03 is equipped with a number of advanced safety features, including lane departure warning, forward collision warning, and active braking. These systems can automatically intervene at critical moments to prevent potential accidents and provide comprehensive protection for occupants.

It also brings great convenience to long-distance driving, ensuring that the vehicle can travel stably on the roadway and reduce driving fatigue. These safety features of the dark blue SL03 not only reflect the manufacturer’s emphasis on occupant safety, but also represent the continuous progress and innovation of modern safety technology.





Cadillac is going to buy the Cadillac XT5, which is cost-effective

There are many options for gasoline + 48V light hybrid system cars now, just as we said today. Let’s take a look together.

Take a look at the appearance of the Cadillac XT5 first. The front style of the Cadillac XT5 looks very personalized and cool. It is equipped with a three-frame middle net, which looks sporty. Then it adopts a sharp headlight design to improve the grade of the whole car. The car is equipped with LED daytime running lights, automatic opening and closing, adaptive far and near light, delayed closing, etc. To the side, the body size of the car is 4813MM*1903MM*1686MM, the car adopts domineering lines, the body gives a very delicate feeling, with large-sized thick-walled tires, smooth lines run through the entire side. On the rear design, the rear of the car looks very fashionable and atmospheric, and the taillights are very sharp, creating a good aura.

Inside the car, the interior looks very cold and rich in functions. The steering wheel of the car is very simple and stylish, made of genuine leather, and the palm fit is very high. Let’s take a look at the central control. The design of the center console is reasonable, which makes the interior style impressive and looks a certain sense of technology. The interior feels good. Let’s take a look at the dashboard and seats. The dashboard of the car presents a deep design style and creates a sporty atmosphere. The car adopts leather seats, which are equipped with functions such as electric adjustment of the sub-seat, electric adjustment of the seat with memory, and seat ratio reclining, which is comfortable.

The Cadillac XT5 trunk space performance is OK. If you have large items on the road, you can put down the rear seats to expand the space. At the same time, the car is equipped with night vision system, brake anti-lock braking (ABS), LED daytime running lights, brake assistance (EBA/BAS, etc.), braking force distribution (EBD) main driver’s airbag, passenger seat airbag, knee airbag, side aircurtain, front side airbag and other safety configurations.

After reading today’s talk, do you have a lot of ideas? Models at this level often offer a good balance of cost performance and practicality, and are often considered by most consumers to be the first choice when buying a car.

Brother Nian’s test drive, is it the icing on the cake to return to basics? Haval’s second-generation big dog

Recently, I believe that the flour who is ready to buy a car has been attracted by the "huge discounts" of various car brands. But I hope that the shrewd people will not be disturbed by the price of their original car demand. For example, SUVs that have always maintained a hot topic in China have always had two groups of loyal fans.

The first group was naturally those who often commuted in the city and occasionally went out to drive. The second group was those who often challenged various difficulty off-road scenarios and often went camping in the wild. But between the two groups, would there be some consumers who needed to commute in the city and go camping on holidays?

I believe the answer is yes.

Of course, it is the second-generation big dog of Haval, the protagonist of our test drive.

I believe that those who are concerned about the Haval brand know that the first generation of Haval Big Dog (Parameters) is launched for young consumers, and its strength is also remarkable. The second generation of Big Dog, based on the advantages of the first generation, increased the length, wheelbase and front wheelbase, allowing the second generation of Big Dog to transform from a compact SUV into a medium-sized SUV.

In terms of power that everyone cares about the most, the maximum horsepower and torque of its 2.0T engine have been improved by 27 horsepower and 50 Nm compared with the previous generation, and the gearbox has also been upgraded from the previous generation’s 7DCT to 9DCT. Whether it is for city driving or off-road scenarios, its acceleration performance, escape ability and fuel economy can be greatly improved. As for other aspects of the second-generation big dog, let’s find out in this test drive.

When I first saw the actual car of the second generation of the big dog, I felt that it was more wild than the first generation. The slender middle net extended directly to the headlights on both sides, making it a tougher look from the newer shape of the previous generation. On the side of the car, the lines clearly engraved on the front and rear fenders give it a sense of muscular power.

In addition, the rivets on the anti-scratch wheel arch will be more obvious than the first generation, making its wild characteristics more prominent. As for why the taillights do not use the most popular through-type taillights, this can only be said to be a matter of opinion. But the headlights and taillights are hidden in the dog bone shape of the turn signal, this small detail is quite interesting.

Sitting in the car of the second-generation big dog, you will first be attracted by its two huge display screens. Its LCD meter is 12.3 inches, and there is a large 14.6-inch central control screen. It can be said that you are directly putting the screen of a mainstream laptop on the center console. And we tested the top model, so there is also a Hud head-up display.

It is worth mentioning that the brightness of this central control screen is as high as 1000 nits, and the hardness has reached the Mohs 7H level, which is not afraid of scratching by daily objects. And it also has three coatings, which can achieve the effects of anti-glare, anti-reflection and anti-fingerprint. It can be seen that in addition to urban use, it also takes into account the use of your off-road scene.

You must know that the most famous national highways such as 318 and 219 are on the plateau, because the daytime sun will be very dazzling. If the brightness of the central control screen is not enough, or there is no anti-reflection function, then when driving in these places, you cannot clearly see the navigation or vehicle status.

Then, in terms of the gear handle, the knob shift of the previous generation has been replaced by the electronic gear shift lever of the tank 300. Next to the gear lever, there are control buttons such as differential lock, handbrake, and knobs for driving mode. There are also physical buttons such as air conditioning and multimedia listed at the bottom of the central control screen. This is to facilitate drivers to perform blind operations in the city or off-road to avoid affecting driving safety.

Of course, the second-generation big dog’s car is equipped with the 8155 chip, and when there is a signal, you can control it by voice to execute various commands. For example, switch on and off the sunroof or windows, adjust the air conditioner, choose songs, check the weather or navigation, etc. Its response is very fast. And you can also speak commands continuously to make it execute, without calling it frequently. Ultimately, its performance is in the same level.

However, what surprised me the most was the comfort of the second-generation big dog seats, both in the front and rear seats, which were excellent. Let me sigh again, what people used to say about the Nissan sofa is really not an advantage now. Look at 100,000 cars like the big dog, it can present a comfortable feeling like the Nissan sofa, and its comfort is that the surface cushion is soft. When you sink in to a certain extent, it will have a support to support you. You wouldn’t say that the whole person is sinking in.

So in this test drive, whether it is on a city road, a country road, or a bumpy mountain road, the big dog gave me a good sense of comfort. Coupled with the longer wheelbase, the legroom in the rear row is also very good. Oh, by the way, I almost forgot to mention that the angle of the rear seat backrest of the first generation of big dogs cannot be adjusted. Now the second-row seat backrest of the second-generation big dog is already adjustable. When you go to Shihe Distance again, the rear passengers can have a more comfortable sitting position and sleep peacefully.

Finally, in terms of some details, the second generation of big dogs has a magnetic camping mosquito repellent lamp, which can also be used as a flashlight or a signal light. There is also a table board in the trunk (to be used with camping carts, etc.), which can be used for 5 people to eat around while camping. The rear window has a rare sunshade of the same class, and the front row has a 50-watt wireless charging. The new cup holder also adopts a shape similar to the fixed seat belt, which is convenient for you to stuff water glasses or drinks of different sizes.

This design, in the process of driving on the mountain road, let me get a real experience. Because when running on the mountain road, the car body shakes because of the bumps in the road, and then my knee directly hits the plastic bottle in the cup holder, which helps me cushion the force. Think about it, if it was a traditional plastic cup holder, it would definitely hurt to hit my knee.

Coming to the driving part, we have to go back to the big dog’s car and talk about its help for off-road driving. I believe those who have played off-road know that off-road depends on the performance of the car and four-wheel drive performance, but also requires the driver’s own excellent driving skills. The second-generation big dog is equipped with a 360-degree panoramic image, plus a 180-degree transparent chassis, and has different visual mode switching, allowing you to clearly see the position of the four wheels on the road, as well as the steering angle.

In addition to the vehicle angle, power output of the four wheels, altitude and other data. It can be said that this is the biggest difference between the second-generation big dog and other city SUVs. I believe that if an off-road white, with the help of this system, he can already challenge some light and moderate off-road sections. If it is an off-road expert, he can even challenge some medium and high-difficulty off-road sections.

Finally, in terms of power, its 2.0T plus 9Dc offers a significant improvement in both power and fuel economy compared to the previous generation of Big Dog. Coupled with its intelligent electronically controlled four-wheel drive, two locks, and nine driving modes, it can really easily respond to urban roads and some off-road road conditions.

In this test drive, we drove on city roads and found that the 9DCT does allow the engine to rotate at a lower speed than the 7DCT at the same speed to increase fuel efficiency. If you don’t drive on city roads like a hardcore SUV, you have to transform into a grease monster/gold swallowing beast. Then on the test drive on the mountain road, there are just one or two hairpin bends, and there will be cross-axles. But we only use the AUTO mode, and the big dog can easily pass these cross axles without the need for locks or other off-road modes at all.

In addition, the big dog is equipped with a tooth-embedded differential lock, which allows you to actively lock, while most of the differential locks of other city SUVs are Eaton’s, which are passive differential locks. It will allow the vehicle to slip for a period of time before intervening, so in terms of escape efficiency, I think the second-generation big dog’s ability to get out of trouble will indeed be stronger. However, the feeling that the second-generation big dog gives me is that its throttle travel will be longer. When you step down, you will find that the depth of the throttle will be a little different from the power you want. You may have to step deeper to achieve the power effect you want. This will take some time to get used to.

After a whole day of test driving, the second-generation big dog gave me the feeling that its power is definitely enough. Whether it is driving on city roads or highways, it is completely fine, and it is easy for beginners to get started. And in the off-road area, if you have a certain off-road foundation, plus the various off-road auxiliary features of the big dog, I think you can also become a bit of a strong off-road expert. Of course, this is only for some intermediate and advanced off-road environments. If you want to challenge some very high shell craters or very steep slopes, then I think you should use a hard-core SUV to go wild.

But if you spend 50% or 60% of your time in the city, as I said at the beginning of this article, and the rest of the time you go out and go wild, then this second-generation big dog is fully capable. And it has been upgraded in technology configuration and all aspects. It is much better than the previous generation, and it is thousands of dollars cheaper. So I think for prospective owners who want to get it all in one step and hope to have both. The second-generation big dog is really an excellent SUV that can balance both urban and off-road environments.

249,900! Changan Qiyuan E07 global pre-sale opens, the most complete configuration analysis

Domestic new energy vehicles are "one-sided", and "interesting" cars like this need to appear, and now, the price and configuration information that everyone is most concerned about is finally here!

Today (September 22), Changan Qiyuan E07 officially opened the pre-sale, the pre-sale price range is 24.99-31 9,900 yuan, the launch of extended range and pure electric version models optional, all standard Changan high-end intelligent driving, equipped with 12 global first configuration, 60 same-level leading configuration and 40 industry first function, product force directly full.

As for the pre-sale rights and interests, for the first 10,000 users who ordered, launched 6 luxury gifts worth 66,000 yuan: including 2,000 to 5,000 cash deduction gifts, equivalent to 3,000 yuan in disguise; Changan high-end intelligent driving function worth 28,000 yuan, directly free for life; and the smart magic carpet set (empty hanging + CDC) worth 20,000, and the technology enjoyment set worth 5,000 is also directly free; more importantly, the whole vehicle, three electricity, air suspension lifetime quality assurance, which can be said to be quite sincere.

At the same time, in order to meet the individual needs of users, the official also launched a series of configuration function options, including matte ink lime optional price of 5,000 yuan; 21-inch wheels + Michelin tires limited time only 10,000 ********lti-functional roof rack optional price of 1,000 yuan, for users who often travel outdoors is very worth choosing.

If you often go out to cross-country to have fun, the official launched a "off-road function set" worth 20,000 yuan, including three functions such as upgrading to and equipping with speed mad bull. For those young people who pursue the trend of technology, the official also launched a "social talent set" worth 20,000 yuan, including four functions such as the star ring front interactive screen and driving pattern. For the "practical party", this configuration is not recommended.

Of course, buying a car is not just for your own enjoyment, but also to take care of your family. To this end, the official specially launched the "Family Comfort Package", including the co-pilot screen, rear seat massage, rear electric adjustment, rear partition electric reclining, electric suction door, flowing water ambient light and exclusive co-pilot and other 6 functions. Considering its 15,000 optional price, individuals still feel that it is worth the money and worth choosing.

From the specific version configuration, the first is the range extension 39Kwh Max intelligent driving version, its pre-sale price is 249,900 yuan. According to the official introduction, the range extension version is equipped with the latest generation of range extension platform independently developed by Changan Quanzhou – Changan Tianyu intelligent range extension, which can effectively reduce the noise and vibration of the range extender.

According to the information previously disclosed, the range extension version will have two versions of single motor and dual motor, equipped with a 1.5T engine as a range extender, and both versions are equipped with a 39-degree golden bell battery, which can provide a battery life of 200 kilometers and 180 kilometers respectively. Since the official did not specify which version this pre-sale is, there may be a lower-priced version in the later stage.

As for the pure electric version, there are two-wheel drive and four-wheel drive models to choose from, respectively, the pure electric 90Kwh Max smart driving version and the pure electric 90Kwh Ultra high-performance version, the pre-sale price is 269,900 yuan and 319,900 yuan respectively, and the price difference between the two versions is 50,000 yuan.

The first is the power performance. Both models are equipped with 800V high-voltage fast charging and a 90-degree battery pack. The CLTC has a battery life of 701km and 650km respectively, but the four-wheel drive high-performance version only takes 3.96 seconds to accelerate 100 kilometers, and the performance acceleration is faster. Thanks to the boost charging technology, the E07 can be charged fast without picking up piles. Charging for 15 minutes supplements the cruising range of 365 kilometers. Coupled with the super power saving function, one click can increase the cruising range by 20%.

In addition to the differences in battery life and performance, the main configuration differences are reflected in the configuration of four-wheel drive off-road, full car massage, and front interactive screen. These configurations are basically based on the optional price, and everyone can choose according to their own needs.

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Write at the end

In a strict sense, the Changan Qiyuan E07 is currently a direct competitor in the market, but from the perspective of price and SUV positioning, the extended-range version is targeted at products such as L7 and L7, while the pure electric version is targeted at Tesla.

As a benchmark product for the Changan brand to move up and enter the 20-400,000 price range for the first time, the burden behind Changan Qiyuan E07 is self-evident. However, the beginning of the article also said that domestic new energy vehicles are "one-sided", and "interesting" cars like Changan Qiyuan E07 need to appear to bring real value to Chinese home users. Now, the pre-sale price of the new car has been released, and consumers who like it can hurry up and place an order first!

BYD Tang 2021 has three versions available for tasting.

  [Smart Car News] On August 17, BYD Tang 2021 was officially launched, with three models: fuel version, DM version and EV version. It is worth noting that the Tang EV version is equipped with BYD’s latest blade battery and will be delivered to customers in the fourth quarter of this year.

  BYD Tang 2021 still adopts Dragon Face family-style design and matrix dzi headlights in appearance design, with fine-tuning in details such as front grille, rims and decorative strips. In addition, this car also has popular design elements such as suspended roof and penetrating taillights.

  In terms of interior, BYD Tang 2021 is equipped with a 15.6-inch suspended central control display and a 12.3-inch full LCD instrument panel, as well as DiLink 3.0 intelligent networking system. This car is equipped with a 2.0T turbocharged engine, and the DM version is equipped with a powertrain consisting of a 2.0T turbocharged engine and a motor. The comprehensive maximum power of the system is 321kW. The pure electric version is equipped with BYD’s latest blade battery.