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　　Beijing Procuratorate Daily, August 26th (Reporter Xie Wenying) "164 votes in favor and 3 abstentions". On the morning of August 26th, the 12th meeting of the 13th the National People’s Congress Standing Committee (NPCSC) voted to pass the newly revised Drug Administration Law. The highlight of the revision is that the scope of counterfeit and inferior drugs has been revised, and drugs imported without approval have not been classified as counterfeit drugs. At the same time, respond to questions such as whether the network can sell prescription drugs.

　　Because China has not implemented compulsory license, some cancer patients are still "illegally" buying foreign generic drugs to save themselves. The experience of Lu Yong, a leukemia patient in Dying to Survive, is a true portrayal of this situation. In order to alleviate the contradiction of "expensive medical treatment" among the people, and let the public use good drugs more quickly and afford good drugs, the State Council requires speeding up the examination and approval of new drugs listed overseas and strengthening the supply guarantee of drugs in short supply, which are all reflected in the newly revised Drug Administration Law.

　　Yuan Jie, director of the Administrative Law Office of the Legal Affairs Committee of the National People’s Congress Standing Committee (NPCSC), said at today’s press conference that the import of drugs from abroad must be approved, which is a rule and principle made by law. Drugs that have not been approved, even those that have been legally listed abroad, cannot be imported. This time, the scope of counterfeit and inferior drugs was revised, and drugs imported without approval were no longer classified as counterfeit drugs, which was a response to the concerns of the people. The newly revised Drug Administration Law stipulates that if the circumstances are minor, the punishment may be reduced or exempted for importing a small amount of drugs legally listed abroad.

　　"It is not the same as reducing the punishment to take drugs imported without approval out of counterfeit drugs and stipulate them separately." Yuan Jie said that the law has strictly set legal responsibilities, and the production, import and sale of counterfeit and inferior drugs without obtaining the drug approval documents are still punished according to the production, import and sale of counterfeit and inferior drugs.

　　To implement the drug administration law well, the responsibility of the regulatory authorities should not be underestimated. Yuan Jie said that in the chapter on supervision and management, it is stipulated that if the drug supervision and administration department finds that a drug violation is suspected of committing a crime, it shall promptly transfer the case to the public security organ. The public security organ, the people’s procuratorate and the people’s court shall promptly transfer the case to the pharmaceutical supervisory and administrative department if there is no need to pursue criminal responsibility or be exempted from criminal punishment according to law, but administrative responsibility should be pursued.

　　There is a high degree of social concern about whether prescription drugs can be sold online. In this regard, the newly revised Drug Administration Law also responded. Liu Pei, director of the Policy and Regulation Department of National Medical Products Administration, said that the current law clearly stipulates that prescription drugs cannot be sold directly to the public through the Internet, and the revised Drug Administration Law stipulates the principle of comparison in selling drugs through the Internet, that is, it requires the drug sales through the Internet to comply with the relevant provisions on drug management, and authorizes the drug supervision and administration department of the State Council to formulate specific measures in conjunction with the health authorities of the State Council and other departments, and stipulates that several types of specially managed drugs cannot be sold online.

　　The newly revised drug administration law will come into effect on December 1 this year.

Ready Player One

Special feature of 1905 film network After four days of release, the box office was 450 million, and the Douban score soared to 9.1.

Completely fired!

This film is adapted from the novel of the same name by the otaku Ernst Klein, and there are hundreds of game movies.

I really can’t think of a more suitable candidate than Spielberg to turn such a book into a blockbuster.

Cover of Ready Player One’s original novels in English and Chinese

Ready Player One is indeed a bestseller and has been translated into 20 languages. However, it caters to some people’s feelings, and at the same time, it is also considered by some readers as "otaku’s cool writing".

Among readers all over the world, some people dislike this book, and some people call it "Wikipedia about the 1980s" — — That is, those eggs are useless for narrative, and the only value is to let readers pat their thighs: ah, I know this!

At that time, Xiao Dianjun was made to want to throw a book by its narrative way of constantly throwing stalks.

The original author was called "the sexiest geek on the planet today" by USA-Today.

But when Spielberg first read this book, he was shocked by the author’s foresight for the future through these stalks. In order to make more people accept it, he injected what he was good at into this "history of popular culture in the 1980 s": longing for the future and trembling; Passion for creativity; There is even an inner observation of a lonely and talented boy.

When it was released in the past, the audience queuing to buy tickets filled several streets, and some people watched it several times.

They all want to immerse themselves in such a scene again:

In john williams’s soundtrack, pterosaurs flew across the sky, and giant Tyrannosaurus rex leisurely crossed the grassland. For the first time, people and ancient creatures hundreds of millions of years ago were separated by only one screen, and their hearts must be filled with awe.

After more than 20 years, we are lucky enough to look at a half-gorgeous and half-barren future through a screen, and we are as excited as those people in those years.

These dreamlike experiences are all attributed to Spielberg. A 72-year-old man, a big child.

As a famous director who has filmed the seventh sci-fi film, five of which have become classics in film history, Spielberg’s talent and imagination are well known. However, few people may notice that after close encounters of the third kind, he stopped writing his own plays, but explored and visualized the works of first-class best-selling novelists.

For example, Melissa Mathison, a female screenwriter, was hired for E.T. Alien, and the inspiration came from Kubrick, who wanted to adapt this short story herself.

Stills of E.T. Alien

Today, Xiao Dianjun wants to talk to you about two other classics — — Jurassic Park and, like Ready Player One, they are adapted from famous science fiction.

As one of the greatest directors of commercial films in Hollywood, Spielberg did this … …

　

Jurassic park

Come on, try Spielberg icing?

Jurassic Park is the first sci-fi film adapted by Spielberg, which comes from michael crichton’s novel of the same name.

　

It created a box office miracle.

After the film was released, it won 900 million dollars at the box office and became the highest-grossing film in history at that time. At that time, there was a crazy dinosaur craze, which inspired a lot of movies featuring dinosaurs and monsters, such as Godzilla in Japan.

　

A movie can sell well in a short time, perhaps just because of IP or dazzling special effects technology. But to become a classic, a solid script has become the top priority.

　

Michael crichton, the author of the original novel, is outstanding in his professional level. The man with a bright resume transferred from Harvard Literature Department to Anthropology Department, and also got a doctor of medicine from Harvard. It is precisely because of this hard-core knowledge of anthropology and medicine that his sci-fi thrillers are horrified … … Especially cultured.

　

Michael crichton, the author of the original novel

The most important genetic engineering technology in Jurassic Park was studied in 1970s. In 1984, scientists cloned gene fragments from the fur of spotted donkey 140 years ago, which proved that DNA can be replicated in inanimate biological tissues. Michael has been paying attention to this field. It took him seven years to publish Jurassic Park in 1990.

After the film was made, someone specially asked Paul Barrett, a dinosaur researcher at the British Museum of Natural History, if the film was all nonsense. The researcher replied: "Many scientific theories in the film are actually reasonable. Even the use of frogs makes sense, because they are quite commonly used laboratory animals in this field, and we know their gene sequences very well. Therefore, Jurassic Park was very avant-garde at that time. "

If such a novel is made into a movie, it must be changed greatly. Coincidentally, it met Spielberg — — Hollywood is the director who will sugar-coat all kinds of hard goods to satisfy the curiosity and security of most audiences.

　

What does Spielberg do?

　

His first step is to make the grandma selling tea eggs on the street understand the original professional and obscure words in the book.

　

For example, there is a classic "dinosaur DNA recovery animation" in the movie. What is said in the book is particularly complicated, but it is shown in a way similar to flash in the movie.

Animation explanation version of DNA restoration

　

Secondly, he will use the most advanced technology to revive the dinosaurs he was obsessed with since childhood, and then Amway will give them to audiences who have never been interested in them.

　

Spielberg once said in an interview: "When I was young, I even dreamed of dinosaurs. Therefore, when filming Jurassic Park, I thought more about my childhood memories and fantasies than the original novel. "

　

His favorite is Triceratops. When he saw Triceratops in a museum when he was a child, he sympathized with it. He once fantasized about what happened to it before it became extinct. So he deliberately set up a sick triceratops when he was filming.

He found the most advanced industrial light and magic studio at that time to build dinosaurs with computer special effects, and a small part of them spent huge sums of money to make models. Among them, the mechanical Tyrannosaurus Rex props weigh 12,000 pounds (about 5.4 tons), which can really crush people to pieces when started.

　

Designers also draw materials from various animals for the movement patterns of dinosaurs. For example, the brachiosaurus, the first appearance in Jurassic Park, is the first creature made entirely by computer special effects in the history of cinema. Its action of lifting its legs off the ground and roaring to the sky is taken from an elephant.

Brachiosaurus was taken from elephants.

　

The last layer of icing, which is also the thickest layer, is on the theme and narrative mode of the novel.

　

As many movie fans know, all the series of Jurassic Park add up, and only one tenth of the content of the novel is selected for adaptation.

　

In addition to too much professional knowledge, the original novel is also a dark, pessimistic and cruel world, full of all kinds of bloody and dark fragments as bad as Alien. In particular, the author’s attitude is calm and merciless. He thinks that there is no essential difference between natural creation of human beings and natural creation of dinosaurs. On the contrary, people make their own decisions to become creators, and the consequences they bring must be borne by themselves.

　

Just like the following fragment in the original work, if it is put on the big screen, it is estimated that many parents will stop their children from entering the cinema.

　

“Elena opened the door. The baby is lying in the cradle of wicker, wrapped in a light blanket, and only his little face is exposed. There are three dark black lizards squatting on the edge of the cradle, just like three grotesque statues. When they saw Elena, they looked up at her curiously, but they didn’t run away. In the light of the flashlight, Elena saw blood dripping from their mouths. A lizard barked softly, lowered its head, shook it quickly and tore a piece of meat from the baby’s face. Elena screamed and rushed forward, and the lizards flew into the darkness. However, as early as when she walked to the front of the cradle, she had already seen what the baby’s face looked like. She knew that the child must have died. "

　

Spielberg added a soft lens to the story. A lot of discussion in this part is omitted, and the main line of the film is taken as the story of the ultimate victory of the great escape of mankind, which promotes the brilliance of human nature. After letting the audience experience the thrill, they breathed a sigh of relief in happy ending.

　

In this way, the whole film is no longer sharp, but has played a psychological soothing role for the American audience at that time.

Minority report

Fans will be disappointed, but I am concerned about the future within reach.

If we say Jurassic Park, Spielberg is wrapping a dark kernel with syrup; Then, for Minority Report, what he did was to pick up a knife and carve the original mysterious shape into an angular shape.

　

After the release of Minority Report, its income was 350 million dollars, which was three times its cost. In the Hollywood Reporter’s best list of films starring Tom Cruise in 2016, the first place was Minority Report.

In fact, if Tom Cruise hadn’t recommended it, Spielberg probably wouldn’t have touched the novel at all. When he made this film, he once said: Philip Dick’s novels are not suitable for most movies, and I’m sure die-hard fans will be disappointed with the movies.

　

If michael crichton, the author of Jurassic Park, is an elite science fiction writer, then Philip Dick is a real diaosi geek. He dropped out of primary school, dropped out of secondary school, and was often in financial distress when he grew up. Writing science fiction became a pillar of his life. He started writing at the age of 27 and died at the age of 53. He published 44 novels and 121 short stories in his life.

Philip dick

　

His novels have a unique temperament and a surprisingly wide range of concerns. Unfortunately, when he was alive, most of his novels were published in some cheap science fiction magazines, and he was poor until he was old, even eating dog food for a time; After his death, he was gradually recognized and became the first science fiction writer recognized by the history of American literature. Blade runner, Total Memory, and the previous TV series Electronic Dream: Philip Dick’s World are all adapted from his novels.

　

Minority Report is one of his short stories, which is extremely short and the theme is very obscure. I guess Spielberg had a big head when he got it.

　

So, how to change it?

　

First, add a 50% murder case first!

　

Spielberg once said, "The success of this film depends on the characters 50% and the mysterious murders 50%."

There are only two murders in the novel Minority Report, but there are five murders in the film.

Although the protagonist in the novel is also a captain, he is an old man in his fifties who worries that his young subordinates will rob him of his seat every day. Tom Cruise, the captain of the film, is handsome and strong, with thick hair and bad habits such as taking drugs.

In order to enrich the plot, besides murder, Spielberg also added many action elements.

For example, fighting

Kidnap (a prophet)

The protagonist in the novel has only one core contradiction in the plot, that is, finding a way out, and has no previous history. However, in the movie, the director added a very deadly pre-historical trauma to the protagonist — — His five-year-old son was abducted by a swimming pool and has been missing ever since.

On the one hand, this design is to add key plots; On the other hand, it also aroused the audience’s sympathy for the protagonist who had been traumatized, and better integrated into this plot that was too cold.

　Tom hanks looked at his son’s holographic projection.

　

Second, carefully build a future world

　

Philip Dick’s sci-fi novels are not only full of brains, but also famous for their imprecise techniques, which may be attributed to his extensive interests, but he has never systematically studied science and technology.

For example, some people laughed at him for still using the old TV set … …

Spielberg-style science fiction films, in addition to the complexity of the plot, must also have technology linked to the most cutting-edge technology at present. He is crazy about creating the "future", and he does not hesitate to make great efforts for it.

　

Starting with E.T. Alien, his way is not only to rely on imagination, but also to find experts to dig into details.

Three years after the film started shooting, he found 15 experts in different fields, including architects, novelists, computer engineers, biological scientists, MIT dean and so on, and brainstormed in a hotel for three days.

He wants these people to give him some advice on how to make a future world that is both convincing and different from ordinary science fiction movies. In three days, they actually worked out an 80-page plan, from architecture to technology.

　

Some inventions they came up with in 1999 have actually come true in today’s world.

　

Such as 3D screen, such as iris recognition authentication.

　

Spielberg described his imaginary future world like this: "The Internet is watching us, and the TV is watching us. We lost our privacy. An advertisement will suddenly appear in front of us and talk to us. "

　

Compared with the pessimism in Philip Dick’s novels, Spielberg is an optimist. He is always full of enthusiasm for new technologies that may come. When talking about this film, he once said: "I hope all the small technologies in the film will come true. We will have pollution-free transportation and newspapers that are automatically updated. "

Third, empathize with the audience, not scare them away.

　

The inspiration of Minority Report comes from Philip Dick’s own anxiety about the Cold War. In the struggle between the two great powers in the book, it is like a miracle that a little person wants to find a way out and survive. The whole novel is like a gloomy joke.

In the movie, the core of this story is replaced by the mainstream values of Hollywood, and it becomes a survival story that people should not lose hope under any circumstances and should fight against fate.

Some scary details in the novel have also been changed to more acceptable settings.

　

For example, in the novel, those prophets are actually mentally retarded and squeezed by the government without human rights. But in the movie, it was changed to a normal person, named after several crime novelists. Agatha, led by Agatha, guided Tom Cruise out of danger again and again with the image of "Goddess".

Changed mental retardation into a goddess

　

These changes have undoubtedly reduced the lingering pessimistic background and self-torture in Dick’s novels, and replaced them with Spielberg’s value that "human nature will always find a way out". If reading the original novel is like witnessing the fate of mankind being hung in the air, Spielberg will finally make everyone who watches it land on his feet and be satisfied.

Over the years, all the children who were shocked by such a big film have grown into middle-aged people, and it seems that Spielberg is the only one who hasn’t changed.

In last year’s documentary Spielberg, Xiao Li commented on Spielberg when he was young:

The child in the Arizona desert kept watching TV and movies, and one day slipped into the film company and found his destiny there. This is a touching Hollywood story in itself.

And Daniel Day Lewis said he was old:

We all have a shelf life, and it slipped away without our knowledge. But this may not be the case for Spielberg. He will love his job until he dies.

　

At least from Ready Player One’s point of view, they are all right.

Original transfer network transformation medical network

[Introduction] Cancer-associated fibroblasts (CAFs) are the key components of tumor microenvironment (TME) and play an important role in regulating cancer progression. However, the underlying mechanism of CAFs activation is still unclear.

On April 8, researchers from the Medical College of Kunming University of Science and Technology published a research paper in the journal Cell Death Discovery, entitled "CXC L12 Alone is enough to reprogram normal fibers into cancer-associated fibers". In this study, the researchers found that cancer-associated fibroblasts (CAFs) significantly induced normal fibroblasts (NFs) to acquire the characteristics of CAFs (called CAFs-like fibroblasts, referred to as CEFs for short), including up-regulating α-SMA and vimentin, enhancing the ability of proliferation and migration, and improving the ability of promoting the migration of lung cancer cells. In vivo, CEFs accelerated the growth of A549 xenograft and induced spontaneous lung metastasis. In particular, inhibition of CXCL12 signaling pathway and STAT3 pathway can reduce the transformation from NFs to CAFs, thus inhibiting the progress of lung cancer in vitro and in vivo. This study revealed that CAFs can promote the transformation of NFs into CAFs-like cells through CXCL12/STAT3 axis, and enhance the growth and metastasis of lung cancer. Therefore, inhibiting CXCL12/STAT3 axis is a promising strategy for the treatment of lung cancer and other CXCL12-dependent malignant tumors.

https://www.nature.com/articles/s41420-025-02420-0#Abs1

Research background

01

Cancer-associated fibroblasts (CAFs) are the main components of tumor microenvironment (TME), which promote tumor proliferation, migration, invasion, epithelial-mesenchymal transition (EMT) and drug resistance by secreting growth factors, cytokines and extracellular vesicles, thus promoting tumor development. CAFs is a large number of fibroblasts with α -smooth muscle actin (α-SMA) positive and activated myofibroblast phenotype. Different from normal fibroblasts (NFs), CAFs has stronger abilities of proliferation, migration and contraction. It is generally believed that CAFs mainly comes from NFs where organizations reside, but the mechanism of transforming NFs into CAFs is still controversial.

More and more evidences show that cancer-associated fibroblasts (CAFs) can be activated by signals from tumor cells and matrix environment, which provides a unique insight into the complex interaction in tumor ecosystem. Researchers found that the hardness of extracellular matrix (ECM) can induce mesenchymal stem cells (MSCs) to differentiate into CAFs, thus promoting the invasion and metastasis of triple negative breast cancer (TNBC). In addition, in gastric cancer, CAFs can also "educate" NFs to promote cancer cell proliferation and T cell inhibition. However, the exact mechanism that drives CAFs activation is still largely unknown. Therefore, detailed research is needed to clarify the molecular mechanism of cancer-related fibroblast activation, so as to open up a new anti-matrix therapy approach.

CAFs promotes the transformation from NFs to CAFs in lung cancer.

02

In order to explore the clinical effect of tumor-associated fibroblasts (CAFs) in the process of transforming normal fibroblasts (NFs) into CAFs in lung cancer, the researchers isolated pairs of CAFs and NFs from tumor tissues or corresponding non-malignant tissues adjacent to tumors of several lung cancer patients. CAFs specifically shows highly expressed vimentin and FAP (known CAFs markers), and its ability to promote the migration of lung cancer cells is stronger than that of NFs from adjacent tissues. Then, NFs was treated with CAFs conditioned medium (CM), and then the characteristics of CAFs were analyzed. The levels of CAF markers α-SMA and vimentin expressed in NFs after CAFs CM education increased significantly. These results indicate that CAFs may be helpful to endow NFs CAFs with specific characteristics.

CAFs induces NFs to acquire CAFs characteristics in lung cancer

conclusion

03

To sum up, this study expounds a new molecular mechanism that the interaction between NFs and CAFs promotes the metastasis of cancer cells. CXCL12/ STAT3 pathway is a key participant in NFs-to-CAFs transition, which provides a key therapeutic target for developing new cancer treatment methods.

References:

https://www.nature.com/articles/s41420-025-02420-0#Abs1

Original title: "New Molecular Mechanism! Kungong medical college: an important therapeutic target of new cancer treatment strategy

Read the original text

　　A recent study published in Cancer magazine found that there is an important correlation between socio-economic status and cancer types. Rich and poor people are prone to different types of cancer.

　　For those who are frightened by the news such as "Julie cuts twice every three years" and "Liver cancer can be inherited", please note that this discovery shows that cancer is the result of the interaction between genetic factors and environmental factors in a long process, just like an egg can’t become a chicken without proper temperature, it is mainly environmental factors. Even if you are related to cancer patients, as long as you pay attention to prevention, it is still possible to shut cancer out!

　　Interview expert: Professor Qin Shukui, vice president of Bayi Hospital and director of the Cancer Center of the whole army.

　　1 Carcinogenic environment leads to the distinction between "rich cancer" and "poor cancer"

　　A recent study published in Cancer magazine found that cancer can be divided into "rich cancer" and "poor cancer".

　　In this study, researchers followed up 3 million cancer cases diagnosed in the United States from 2005 to 2009, covering 42% of the population in the United States and covering the richest and poorest communities in the United States.

　　The results show that there is an important correlation between socio-economic status and cancer types. Richer people are more likely to suffer from melanoma, thyroid cancer, skin cancer and testicular cancer; The poorer people are more likely to suffer from Kaposi sarcoma, laryngeal cancer, cervical cancer, penile cancer and liver cancer.

　　Why is this so?

　　The reason is that the causes of cancer (environment and living habits) are different, and eventually different types of cancer will be produced.

　　Cancer is the result of the interaction of heredity and environment.

　　Case: There is a family. The eldest son was admitted to the university and went to other places, and then he stayed to work in other places, while the youngest son stayed with his mother all the time. Later, the mother died of cancer, and then, the youngest son died of cancer.

　　This case shows that there are genetic defects in cancer families, but "common living environment and way" may play an important role.

　　Case: Ms. Leah in Britain divorced her husband because of rectal cancer. She believes that her husband likes red meat, drinks and spicy food, and has a bad temper, insists on smoking and is getting obese year by year. This lifestyle will affect her and her children, and she wants to get rid of this living environment.

　　There is an article in the British Medical Journal detailing "marital diseases", saying that if one of the spouses is sick, the prevalence rate of the other will increase a lot, from cancer, diabetes, hypertension to ischemic heart disease. The reason is that people who live together for a long time have many diseases at the same time because of the same eating habits and similar lifestyles.

　　Modern genetics shows that cancer depends not only on genetic factors, but also on "being affected by acquired carcinogens and cancer promoters". Breast cancer, lung cancer, liver cancer, esophageal cancer, cervical cancer and colorectal cancer are greatly influenced by bad living habits and environmental factors.

　　China also has "poor cancer" and "rich cancer"

　　Case: The 31-year-old "True Water Without Fragrance" (net name) has been feeling intense nausea for more than a month. She usually pays great attention to maintaining her health. She eats miscellaneous grains for breakfast every day, drinks tea and doesn’t touch alcohol and tobacco. She has regular physical examination every year and has never had any major problems. This time, she thought vomiting was a sign of pregnancy, but after a check, the result was: advanced rectal cancer!

　　"True water has no fragrance" slowly pieced together the clues of his illness: although he sometimes eats miscellaneous grains, he eats a lot of meat, and he rarely exercises. He is 155 cm tall but 128 kg fat. At this time, her mother told her that her grandmother died of esophageal cancer, her grandfather died of lung cancer, and an uncle also had rectal cancer!

　　Her grandmother’s esophageal cancer belongs to "poor cancer" and her rectal cancer belongs to "rich cancer".

　　What are the poor and rich cancers in China?

　　"Poor cancer" also includes liver cancer, stomach cancer, esophageal cancer and cervical cancer. "Cancer-rich" also includes lung cancer, colorectal cancer, breast cancer, lymphoma and prostate cancer.

　　4 "poor cancer" is related to long-term chronic infection.

　　Why do liver cancer, gastric cancer, esophageal cancer and cervical cancer belong to "poor cancer"?

　　A study in the Annals of Oncology shows that some cancers can be caused by long-term chronic infection. In China, hepatitis B virus, Helicobacter pylori, human papillomavirus (HPV) and EB virus are the most common infectious and carcinogenic factors.

　　Infected with hepatitis B virus, it further evolves into cirrhosis through acute and chronic inflammation, and a small number of patients can eventually lead to liver cancer.

　　Helicobacter pylori is the most common infectious bacteria, which may cause gastritis and peptic ulcer, and long-term infection may promote gastric cancer.

　　The bane of cervical cancer and its precancerous lesions has been proved to be human papillomavirus infection.

　　The high incidence of nasopharyngeal carcinoma is closely related to EB virus infection.

　　Generally speaking, these cancers related to long-term chronic infection mostly occur in economically underdeveloped areas, where the natural environment is often bad, the nutritional conditions are poor, the hygiene level is low, and the living habits are not good. Therefore, these cancers are easy to develop.

　　5 "cancer-rich" is related to modern lifestyle.

　　Why are lung cancer, colorectal cancer, breast cancer, lymphoma and prostate cancer called "rich cancers"?

　　Rectal cancer with "true water without fragrance" is regarded as a typical "cancer-rich". In terms of pathogenesis, colorectal cancer is influenced by related genes, such as diabetes, hypertension and coronary heart disease. Lifestyle, perennial high-fat diet, lack of dietary fiber intake, sedentary inactivity, untimely defecation or habitual constipation are all common causes.

　　Why excessive intake of high-fat food is one of the carcinogenic factors?

　　A new study found that a high-fat diet can change the intestinal microecology (that is, microbial composition)-some bacteria increase, while others decrease. As a result, the immune defense against intestinal cancer is reduced, and the incidence of cancer is increased.

　　Why sedentary, more susceptible to cancer?

　　The immune function in human body is enhanced with the increase of activity, and sedentary can make the human body lack enough immune cells.

　　An epidemiologist in Canada found that in the United States, 49,000 cases of breast cancer and 43,000 cases of colon cancer are associated with inactivity every year, and breast cancer and colon cancer seem to be two cancers closely related to exercise.

　　Blocking infection can effectively prevent "poor cancer"

　　6 How to prevent "poor cancer"?

　　There is no direct causal relationship between infection and cancer, and it will not be "killed in one blow". Viruses and germs lurk quietly in our bodies, waiting for an opportunity to attack. This process takes about 10 years or more. If we can stop their spread and eliminate them in the cradle, we can effectively prevent the occurrence of cancer.

　　First, get vaccinated. According to statistics, 95% of infants and children in a certain area were injected with hepatitis B vaccine in 1984. Twenty years later, the number of hepatitis B carriers dropped from 10% to 20% to 0.2%, and the incidence of liver cancer decreased by 70% to 80%.

　　Second, early treatment. Helicobacter pylori can be completely eradicated by antibiotic combined therapy, which can not only relieve gastritis and gastric ulcer, but also play a good role in resisting the further development of gastric cancer.

　　Third, do screening. Women over the age of 30 must have regular cervical screening. At the same time, protect yourself, pay attention to using condoms, don’t have sex too early and limit the number of partners.

　　Finally, the dining system. Helicobacter pylori and other germs are highly contagious, and can be transmitted through hands, food and tableware. It is also best to implement a separate meal system in family life.

　　Healthy lifestyle can prevent "cancer-rich"

　　7 How to prevent "cancer-rich"?

　　"Cancer-rich", such as colorectal cancer, breast cancer and lymphoma, has no unique and significant inducement, and some people think it is difficult to prevent it.

　　However, this kind of rich disease also has some common causes-eating too much, eating a high-fat and high-protein diet, and lack of exercise.

　　Therefore, the way to prevent it is to establish a healthy lifestyle. Compared with the "poor cancer" caused by chronic infection, it is more difficult to do and requires greater determination and perseverance! (Li Lanling)

　　CCTV News:On June 15th, the State Council held a press conference on the operation of the national economy in May 2023. Fu Linghui, spokesperson of the National Bureau of Statistics and director of the comprehensive statistics department of the national economy, said at the meeting that from the situation in May, the growth rate of the main production demand indicators has improved to varying degrees. Since the beginning of this year, with the full recovery of normal operation of the economy and society, the previously suppressed production demand has rebounded. Judging from the situation in various countries, there will be a rebound after the economic operation returns to normal operation. With the economic operation gradually returning to normal operation, it will gradually enter a steady recovery trend. Judging from the current situation, due to the low base last year, the economic growth in the second quarter was significantly faster than that in the first quarter. In the third and fourth quarters, with the improvement of the base, the economic operation will return to the normal growth level. From the perspective of the whole year, there are many favorable supports for the economy to achieve its expected development goals throughout the year. There are mainly the following aspects:

　　First, the role of consumption has gradually increased. Since the beginning of this year, China’s consumption potential has been gradually released, and its pulling effect on economic growth is increasing. In the first quarter, the contribution rate of final consumption expenditure growth to economic growth has reached 66.6%. From January to May, the year-on-year growth rate of total retail sales of social consumer goods was 3.5 percentage points faster than that in the first quarter. Service consumption is growing well. From January to May, the national box office revenue increased by more than 40% year-on-year, and the catering revenue increased by 22.6%. During the May 1 holiday, residents’ travel increased significantly, which led to the expansion of related consumption. At present, the overall improvement of the employment situation is conducive to increasing residents’ income and improving their spending power. Various departments actively introduce policies to promote consumption, which will enhance residents’ willingness to consume. The deep integration of online and offline consumption and the accelerated development of new consumption formats and new models are also conducive to expanding consumption. The strengthening of consumption will effectively promote economic recovery.

　　Second, the accumulation of innovation kinetic energy has increased. Since the beginning of this year, China has deeply implemented the innovation-driven development strategy, actively promoted the self-reliance and self-improvement of science and technology, and the development trend of high-end, intelligent and green production is obvious, and the development of new kinetic energy has grown stronger. From January to May, the added value of equipment manufacturing above designated size increased by 6.8% year-on-year, and the production index of information transmission, software and information technology services increased by 11.3%, all of which maintained rapid growth; The output of industrial control computers and systems and polysilicon increased by 33.4% and 84.2% respectively. The pace of green and low-carbon transformation has accelerated, and new energy products have grown rapidly. From January to May, the output of solar cells increased by 53.6% year-on-year, and the kinetic energy of innovation and development increased, which will effectively promote industrial upgrading and development, accelerate the formation of a modern industrial system, promote the transformation of economic growth momentum, and lay a solid foundation for the stable and healthy development of China’s economy.

　　Third, the dividend of reform and opening up continues to emerge. Since the beginning of this year, China has deepened the reform of key areas and key links, actively promoted the construction of a high-standard market system, accelerated the construction of a unified national market, steadily expanded institutional opening, accelerated the creation of a market-oriented and legalized international business environment, vigorously stabilized the trade of traditional trading partners, and actively expanded economic and trade cooperation with RCEP and countries along the Belt and Road Initiative, with continuous results. From January to May, China’s total import and export volume of goods increased by 4.7% year-on-year, and the total import and export volume with countries along the Belt and Road increased by 13.2%. Judging from the utilization of foreign capital, the actual utilization of foreign capital in China’s high-tech industries increased by 12.8% from January to April.

　　In the next step, comprehensively deepening reform, expanding high-level opening up and steadily advancing will inject strong impetus into economic development. Of course, we must also see that the current international environment is complex and severe, the recovery of the world economy is still weak, the spillover effect of policy contraction in major developed economies appears, and there are many unstable and uncertain factors. Insufficient domestic market demand, lower prices, more difficulties for business entities, and weak foundation for economic recovery. Despite the pressure and challenges, the fundamentals of China’s long-term economic improvement have not changed, and the characteristics of strong resilience, great potential and wide space are obvious. Since the economy and society have fully resumed normal operation, macroeconomic policies have made concerted efforts, and economic operation has recovered and high-quality development has steadily advanced.

CCTV News:During the "Eleventh" holiday, the reporter visited various places and learned that both the new car sales market of new energy vehicles and the second-hand car trading market showed a rising trend. In addition, with the support of a number of favorable policies, consumer enthusiasm continues to rise.

This holiday, Mr. Zhou, who lives in Nanjing, Jiangsu Province, bought a new energy vehicle worth 330,000 yuan, according to "the price of a single vehicle is 300,000 yuan — Mr. Zhou can get a subsidy of 6,000 yuan for the standard of subsidizing 6,000 yuan below 400,000 yuan.

During the "Eleventh" holiday, consumers in Dezhou, Shandong Province can enjoy a one-time subsidy ranging from 3,000 yuan to 6,000 yuan when purchasing new energy passenger cars. In addition, they are exempted from the purchase tax of 4.5% of the car price, the travel tax in 360 yuan, and the replacement subsidy of up to 6,000 yuan and the cash benefit of up to 20,000 yuan given by manufacturers, which makes many consumers feel excited.

Not only the new car market, this holiday, the second-hand car trading market is also stimulated by the policy, and the trading volume has risen linearly. The reporter visited the used car trading market in Huaxiang, Beijing, and learned that the transaction volume of car inspection and transfer has increased by 30%. On October 1 this year, the Ministry of Public Security and other departments issued a policy that when a registered automobile sales enterprise applies for the transfer registration of a small non-operating used car, the public security organ will implement separate endorsement management and issue a temporary license plate. For cities where automobile purchases are restricted, it is clear that used cars purchased by automobile sales enterprises and used for sales do not occupy the number plate index. At the same time, all regions strictly implement the policy of completely canceling the restrictions on the movement of used cars, and cancel the restrictions on the movement of small non-operating used cars that meet the national five emission standards nationwide (including the national key areas for air pollution prevention and control) to promote the free circulation of used cars and cross-regional operation of enterprises.

According to the data of China Association of Automobile Manufacturers, in 2022, the production and sales of new energy vehicles will reach 3.97 million and 3.86 million respectively in the first eight months, up by 120% and 110% respectively.

　　The National Health and Wellness Committee held a press conference on the 10th to introduce the prevention and treatment of respiratory diseases in winter.

　　It is still recommended to vaccinate against influenza if symptoms are not diagnosed and self-healing.

　　Fever, cough, runny nose … After these flu-like symptoms appear, if you don’t go to the hospital to be diagnosed with the flu, do you still need to get the flu vaccine after recovery? When is the vaccination? Xia Gang, director of the Department of Health and Immunity of the National CDC, responded to the suggestion that this situation should still be vaccinated against influenza.

　　Xia Gang explained that there are two main reasons. First, the symptoms of respiratory infection are not specific, and many pathogenic infections may have flu-like symptoms such as fever and headache. However, these symptoms are not necessarily caused by influenza virus, but also by other pathogens, the most common of which is the common cold.

　　Second, there are many types and subtypes of influenza virus that can cause epidemic. After being infected with a certain type or subtype, you may be at risk of being infected with other types or subtypes. For example, if you have been infected with influenza A, you may still be infected with influenza B. The influenza vaccine is a multivalent vaccine covering many different types and subtypes, that is, the commonly used trivalent and tetravalent vaccines. If you are infected with a certain type of influenza and vaccinated with influenza vaccine containing other types of influenza components, you can still play the role of vaccine in preventing this type of influenza.

　　In addition, in the same epidemic season, there are usually different types and subtypes of influenza viruses co-prevalent. At present, the main subtype is influenza A (H3N2), followed by influenza B.. In the past, in the same epidemic season, the dominant strains were gradually transformed from one type to another.

　　Xia Gang stressed that even if there are flu symptoms recently, it is recommended to get flu vaccine as soon as possible after recovery.

　　The overall amount of diagnosis and treatment of children’s respiratory diseases in medical institutions above the second level in China showed a downward trend.

　　Mi Feng, spokesperson of the National Health and Wellness Commission, said that in view of the current high incidence of respiratory diseases, especially children’s respiratory diseases, the National Health and Wellness Commission, state administration of traditional chinese medicine and the National Bureau of Disease Control and Prevention have continuously strengthened monitoring and judgment, dispatched the supply and diagnosis of medical resources in various places, guided the overall deployment of medical resources within and between medical institutions, increased relevant consulting rooms and treatment areas according to the number of patients, and expanded ward resources. Guide secondary hospitals, maternal and child health hospitals, traditional Chinese medicine hospitals, and primary medical and health institutions to "open as much as possible", extend the consultation time, optimize the in-hospital diagnosis and treatment process, improve service efficiency, and effectively protect the needs of pediatric diagnosis and treatment.

　　Mi Feng introduced that at present, the overall amount of diagnosis and treatment of children’s respiratory diseases in medical institutions above the second level in China has shown a downward trend, and the increase in pediatric diagnosis and treatment in some large children’s specialist hospitals and general hospitals has been alleviated to some extent.

　　Judging from the overall situation of fever clinics and emergency departments, the number of patients with respiratory diseases in China has been relatively stable in recent days, especially in primary medical institutions. The overall normal medical services in the country have not been affected.

　　Mi Feng stressed that it is necessary to give full play to the role of medical associations, medical associations, medical groups and Internet medical care, establish a mechanism for collaboration between general hospitals and primary medical institutions, expert sinking and patient referral, and divide patients into different levels to facilitate patients to choose medical treatment reasonably.

　　It is necessary to give full play to the characteristics and advantages of traditional Chinese medicine and combine traditional Chinese and western medicine to improve the prevention and treatment effect.

　　Primary and secondary schools, kindergartens, nursing homes, social welfare homes and other key places and crowded places should implement measures such as ventilation and disinfection, strengthen health science popularization and health monitoring, do personal protection, reduce the spread of diseases and reduce the risk of infection.

　　We should continue to do a good job in vaccination and constantly optimize vaccination services.

　

Municipalities and Guangde City, susong county Human Resources and Social Security Bureau, Development and Reform Commission, Housing and Urban-Rural Development Bureau (Urban-Rural Development Bureau), Transportation Bureau, Water Conservancy (Water Affairs) Bureau, Municipal Telecom Infrastructure Co-construction and Sharing Office (Communication Development Office), China People’s Bank’s downtown branches, and all banking supervision branches:

The measures for the implementation of wage guarantee for migrant workers in the field of engineering construction in Anhui Province are hereby printed and distributed to you, please implement them.

　

　

　

Anhui Provincial Department of Human Resources and Social Security Anhui Provincial Development and Reform Commission

　

　

　

Anhui Provincial Department of Housing and Urban-Rural Development Anhui Provincial Department of Transportation

　

　

　

Anhui Provincial Department of Water Resources Anhui Provincial Communications Management Bureau

　

　

　

China People’s Bank Hefei Central Branch China China Banking and Insurance Regulatory Commission Anhui Supervision Bureau

　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　March 18, 2022

　

　

　

　

Wage security deposit for migrant workers in the field of engineering construction in Anhui Province

measures for the implementation

　

Chapter I General Provisions

the first　　In order to protect the wage rights and interests of migrant workers according to law, optimize the business environment, and play an important role in solving the problem of wage arrears for migrant workers, according to the Regulations on the Protection of Wage Payment for Migrant Workers (Order No.724 of the State Council), the Notice on Printing and Distributing the Provisions on Wage Guarantee for Migrant Workers in the Field of Engineering Construction (No.65 issued by the Ministry of Human Resources and Social Security [2021]) and the Provisions on Wage Payment in Anhui Province (Order No.194 of the provincial government), etc.

the second　　As mentioned in these Measures, the wage guarantee for migrant workers (hereinafter referred to as wage guarantee) refers to the general contractor in the field of engineering construction (includingProfessional contracting enterprises that directly contract construction units to contract projects set up accounts in the bank and store them according to a certain proportion of the project construction contract amount, which is specially used to pay special funds for migrant workers who provide labor for contracted projects.

Wage deposit can be replaced by bank guarantee or guarantee insurance issued by financial institutions, and the introduction of guarantee company guarantee can be explored in areas where conditions permit. Actively develop electronic guarantee (insurance policy).

Article　　These Measures shall apply to the storage proportion, storage form, reduction and exemption measures and the use and return of wage deposits in the field of engineering construction.

Article 4　　The provincial administrative department of human resources and social security is responsible for organizing the implementation of the unified wage guarantee system in the province, relying on the supervision information system for ensuring the wage payment of migrant workers in the province, and implementing digital and process management of wage guarantee storage.

The administrative departments of human resources and social security at all levels should establish and improve the consultation mechanism with the local industrial engineering construction departments and financial supervision departments, strengthen information notification and law enforcement cooperation, and ensure the standardized and smooth operation of the wage guarantee system.

Article 5　　Wage margin by the municipal or county human resources and social security administrative departmentSpecific managementWhen conditions are ripe, it will gradually transition to the provincial administrative department of human resources and social security.manage.

Municipal or county-level human resources and social security administrative departments that implement specific management, hereinafter referred to as "territorial human resources and social security administrative departments"; The corresponding administrative regions are hereinafter collectively referred to as "wage deposit management regions".

The geographical location of the same project involves two or more.manageArea, designated by the common administrative department of human resources and social security at the next higher level, and the competent department of industrial engineering construction at the same level.

Chapter II Storage of Wage Margin

Article 6　　General contracting of constructionunitThe wage deposit shall be stored in the bank where the project is located, and a bank guarantee or guarantee insurance may also be applied for.

Article 7　　The bank handling the wage margin (hereinafter referred to as the handling bank) shall meet the following conditions for opening, storing, inquiring, withdrawing, canceling the account and opening a letter of guarantee for the wage margin account according to law:

(1) There is a legal person institution of a commercial bank or its authorized branch in the wage guarantee management area where the project is located;

(2) It has a good credit rating and excellent service level, and promises to provide wage guarantee business services in accordance with regulatory requirements.

Article 8　　An insurance company handling the wage deposit shall meet the following conditions for underwriting, inquiring, settling claims and issuing policies and insurance certificates for the performance guarantee insurance of migrant workers’ wage payment according to law:

(a) there is an insurance company legal person institution or its authorized branch in the wage deposit management area where the project is located;

(2) It has a good credit rating and excellent service level, and promises to provide special insurance products (one-year and multi-year) for the performance of wage payment for migrant workers filed in China Banking and Insurance Regulatory Commission, China in accordance with regulatory requirements.

Article 9　　General contracting of constructionunitIt shall, within 20 working days from the date of obtaining the construction permit (approval of the commencement report) of the project (within 20 working days from the date of signing the construction contract for the project that does not need to apply for the construction permit and approve the commencement report according to law), hold the business license, the construction contract signed with the construction unit and the differentiated deposit certification materials, and open a special account for wage deposit in the handling bank to store the wage deposit. The name of the special account is the name of the construction general contractor plus the name of the project plus the "special account for wage deposit".

If the general contractor has two or more projects under construction in the same wage margin management area, it may open a new special account, or manage the projects separately under the existing special account, provided that it meets the regulatory requirements of the project location.

For the project contracted by the consortium, the construction unit and the contractor agree in the contract agreement on the deposit subject, sharing and method of the wage deposit. If there is no agreement, the organizer or leader of the consortium will store the wage deposit.

Article 10　　General construction contract for storing wage depositunitThe Agreement on Deposit of Migrant Workers’ Wages shall be signed with the handling bank (Annex 1), and a copy of the Agreement shall be sent to the local administrative department of human resources and social security for the record.

Article 11　　The handling bank shall standardize the work of opening a wage margin account, provide necessary convenience for storing the wage margin, verify the nature of the account with the account opening unit, make special marks on the wage margin account in the business system, and make overall restrictions on seizure, freezing or transfer settings on relevant network inspection and control platforms and electronic special line information transmission systems to prevent improper seizure, freezing or transfer, and ensure the safety of funds.

Article 12　　The wage deposit shall be stored according to a certain proportion of the project construction contract amount (or annual contract amount), and shall be distinguished according to the following circumstances:

(1) If the contract amount is more than 300 million yuan (inclusive), the storage ratio of wage deposit shall be 1%, and the storage amount shall not exceed 5 million yuan;

(two) the contract amount is less than 300 million yuan, the wage deposit storage ratio is 2%, and the storage amount is not more than 3 million yuan.

Article 13　　In any of the following circumstances, the wage deposit shall be managed in a differentiated manner:

(1) General contracting of constructionAfter the unit stores the wage deposit or submits the bank guarantee and guarantee insurance, it undertakes the construction of the project in the wage deposit management area.In a certain period of time, if there is no wage arrears, the real-name management of employment and the special account for migrant workers’ wages are implemented as required, or if the employee has obtained the title of labor security integrity demonstration unit, excellent construction enterprise and A-level evaluation of labor security integrity level, after application, the salary deposit for the new project should be reduced or exempted from storage.

1. If there is no wage arrears for two consecutive years and the real-name management of employment and the special account system for migrant workers’ wages are implemented as required, the storage ratio of wage deposit will drop by 50% (the starting date will be calculated retrospectively from the date of application);

2. If there is no wage arrears for three consecutive years and the real-name management of employment and the special account system for migrant workers’ wages are implemented as required, the wage deposit is exempted (the starting date is calculated retrospectively from the date of application);

3. Provincial labor security integrity demonstration units are exempt from storing wage deposits within 3 years in the whole province, and municipal labor security integrity demonstration units are exempt from storing wage deposits within 3 years or credit rating A-level enterprises within 1 year in the administrative area of this Municipality (counting time is calculated from the date specified in the integrity demonstration unit certificate or the date of release of rating evaluation);

4. Excellent construction enterprises at the provincial level are exempted from storing wage deposits within 2 years in the whole province, and excellent construction enterprises at the municipal level are exempted from storing wage deposits within 2 years in the administrative area of this Municipality (counting from the date specified in the certificate of excellent construction enterprises).

(2) The general contractor of construction has more than 3 projects under construction in the same wage deposit management area, and the storage ratio will be lowered by 0.5% on the basis of differentiated deposit, but not less than 0.5% of the construction contract amount.

If the construction contract amount is less than 3 million yuan, and the general contractor of the project has not defaulted on the wages of the project undertaken within one year before the signing of the construction contract, it is exempt from storing the wage deposit.

(3)General contracting of constructionunitWage arrears occurred in the construction project in the wage margin management area within 2 years before storing wage margin or submitting bank guarantee and guarantee insurance.　The proportion of wage deposit storage increased by 50%; If the wage arrears of migrant workers are included in the "list of serious untrustworthy subjects", the proportion of wage deposits will increase by 100%; After the increase, it is not limited by the upper limit of storage amount.

Article 14　　General contracting of construction that meets the conditions of reducing or exempting wage deposit.unit, a written application shall be submitted to the local administrative department of human resources and social security (Annex 2), and the local administrative department of human resources and social security shall review and give a written reply within 3 working days, and issue the Certificate of Differentiated Deposit of Wage Margin for Migrant Workers (Annex 3). Audit should be comprehensive construction general contracting.unitDaily inspection of honesty and law-abiding, clues about unpaid wages reflect the handling of cases on the platform, and the implementation of the wage payment guarantee system in the wage payment supervision information system for migrant workers.

Article 15　　The storage ratio of wage margin can be dynamically adjusted regularly according to the actual situation of ensuring the wage payment of migrant workers in this province, and announced to the public on its own initiative.

Article 16　　The principal and interest in the wage guarantee account belong to the construction general contractor who opened the account.unitAll. During the period when the wage deposit account is supervised, the enterprise can freely withdraw and use the interest and other lawful income of the wage deposit.

Except in accordance with the provisions of Article 22 of these Provisions, no other unit or individual may use the principal in the wage guarantee account.

Article 17　　The general contractor of construction adopts bank guarantee or guarantee insurance instead of cash to store wage deposit, and the amount of guarantee or insurance of guarantee is equal to the amount of wage deposit stored in cash.

The original bank guarantee and guarantee insurance certificate (Annexes 4 and 5) shall be submitted to the local administrative department of human resources and social security for preservation.

Article 18　　The bank guarantee shall be in favor of the local administrative department of human resources and social security, and the nature of the guarantee is irrevocable on demand.

Guarantee insurance replaces wage deposit, and the local administrative department of human resources and social security has the right to claim insurance money on behalf of the insured, and finally pays it to the insured.

Article 19　　General contracting of constructionunitEffective letter of guarantee and insurance shall be provided during the construction period of the project, and the validity period of the letter of guarantee and insurance shall be at least one year and exceed the construction contract period by more than 90 days (inclusive). If the unfinished letter of guarantee and insurance of the project expire, the general construction contract will be made.unitA new letter of guarantee and insurance shall be replaced or the validity period of the letter of guarantee and insurance shall be extended one month before its expiration.

Article 20　　In accordance with the provisions of differentiated storage, the construction general contracting unit that has reduced or exempted the wage deposit has the problem of wage arrears for migrant workers, and if the circumstances are serious and cause adverse social impact, it shall re-store the wage deposit in accordance with the provisions of wage deposit storage.

Article 21　　The local administrative department of human resources and social security shall store the wage deposit or open a bank guarantee and guarantee the general construction contract.unitThe list and the corresponding project name shall be announced to the public, and the construction general contracting enterprise shall incorporate the implementation of the wage guarantee system in this project into the content of the rights protection information bulletin board.

Chapter III Use of Wage Margin

Article 22　　General contracting of constructionunitIf the contracted project is in arrears with the wages of migrant workers, the administrative department of human resources and social security of the territory shall make an administrative decision to order it to pay off within a time limit or pay off in advance, and the general construction contract shall be made.unitIf the local human resources and social security administrative department refuses to perform at the due date, it may issue the Notice of Payment of Wage Margin for Migrant Workers (Annex 6, hereinafter referred to as the Notice of Payment) to the handling bank, and notify the relevant general construction contractor and the handling bank in writing. The handling bank shall, within 5 working days after receiving the Notice of Payment, pay the corresponding amount of money from the wage guarantee account to the migrant workers who are in arrears of wages designated by the local administrative department of human resources and social security by bank transfer.

General contracting of constructionunitWhere the bank guarantee or guarantee insurance is used to replace the wage deposit, the agency providing the bank guarantee or guarantee insurance shall pay the wages of migrant workers in accordance with the bank guarantee and guarantee insurance agreement within 5 working days after receiving the Notice of Payment.

Article 23　　After the wage deposit is used, the general construction contract will be made.unitThe wage deposit shall be replenished within 10 working days from the date of use.

Where the bank guarantee or guarantee insurance is used to replace the wage deposit, the general construction contract will be undertaken.unitA new letter of guarantee with the same scope and amount of guarantee as the original letter of guarantee, new insurance with the same scope and amount of insurance liability as the original insurance shall be provided within 10 working days, or the wage deposit shall be stored in cash. After the construction general contractor opens a new letter of guarantee and insurance, the original letter of guarantee and insurance liability shall become invalid.

Article 24　　Where the wage deposit is stored in cash, the handling bank shall provide the wage deposit statement to the construction general contractor and the local human resources and social security administrative department every quarter.

Article 25　　After the completion of the project corresponding to the wage deposit, the general contractor of the construction makes a written commitment that there is no unresolved problem of wage arrears for migrant workers in this project, and can apply for returning (canceling) the wage deposit or returning the original bank guarantee and guarantee insurance certificate 30 days after the rights protection information bulletin board on the construction site and the portal website of the local human resources and social security administrative department are publicized.

The local administrative department of human resources and social security shall complete the examination within 5 working days after the general contractor submits the written application (Annex 7), and issue the Confirmation Letter of Return (Cancellation) of Wage Margin for Migrant Workers within 3 working days after the examination (Annex 8). After the handling bank receives the confirmation letter, the wage deposit account will be deregistered, and the corresponding funds will no longer belong to the wage deposit. The general contractor can freely dispose of the account funds or cancel the account.

If the bank guarantee or guarantee insurance is used to store the wage deposit instead of cash, and it complies with the provisions of the first paragraph of this article, the local administrative department of human resources and social security shall undertake the general construction contract.unitSubmit a written application and review it within 5 working days, and return the original bank guarantee and guarantee insurance certificate within 3 working days after review.

The local administrative department of human resources and social security finds that there is an unresolved problem of wage arrears for migrant workers in the corresponding project during the audit, and should inform the general contractor in writing within 3 working days after the audit is completed. After the general contractor performs the responsibility of paying off (paying off first) according to law, it can submit a written application for returning (canceling) the wage deposit or returning the original bank guarantee and guarantee insurance certificate again.

Article 26　　The local administrative department of human resources and social security shall establish a regular (at least once every six months) check mechanism for the wage guarantee. If it is verified that the project is completed and there is no problem of wage arrears for migrant workers, the general contractor of construction fails to submit the application for return within a certain period of time, it should take the initiative to start the return procedure.

Article 27　　General contracting of constructionunitIf an administrative act of an administrative department damages its lawful rights and interests, it may apply for administrative reconsideration or bring an administrative lawsuit to a people’s court according to law.

Chapter IV Supervision of Wage Margin

Article 28　　The competent department of industrial engineering construction shall inform the relevant units in writing to store the wage deposit in time when issuing the construction permit or approving the commencement report, and feed back the basic information of the project to the local administrative department of human resources and social security in writing within 3 working days.

Article 29　　The wage deposit shall be earmarked for special purposes, except for paying off (paying off first) the general construction contract.unitThe contracted projects shall not be used for other purposes except the wages owed to migrant workers.

Unless otherwise provided by law, the wage deposit shall not be sealed up, frozen or allocated for reasons other than paying the wages of migrant workers who provide labor for this project.

Article 30　　The administrative department of human resources and social security should strengthen supervision and control over the general contracting of construction.unitFailing to store or supplement the wage deposit (or provide or update the guarantee and guarantee insurance) according to the Regulations on the Protection of Wage Payment of Migrant Workers and these Measures, the legal liability shall be investigated in accordance with the provisions of Article 55 of the Regulations on the Protection of Wage Payment of Migrant Workers.

For the general construction contract that fails to implement the wage guarantee system according to the regulations.unitIn addition to administrative punishment (handling) according to law, it should be included in its credit record in accordance with relevant regulations, and credit punishment should be implemented according to law.

If banks, insurance companies and other agencies fail to handle the wage guarantee business according to the regulations, the provincial human resources and social security administrative department will take regulatory measures in conjunction with the financial regulatory department according to law.

Article 31　　The administrative department of human resources and social security in the territory should establish a wage guarantee management ledger, strictly regulate the financial and auditing systems, strengthen account supervision, and ensure earmarking. The management ledger should include relevant information such as the storage, filing, use and return of the wage margin, and be included in the management of the supervision information system for ensuring the wage payment of migrant workers.

The competent department of industrial engineering construction shall promptly notify the administrative department of human resources and social security at the same level of the problem of failing to store the wage deposit according to the regulations found in the daily supervision and inspection.

If the administrative department arbitrarily reduces or exempts, collects over the limit, misappropriates illegally, or delays the return of the wage deposit without any reason, the responsibility shall be seriously investigated, and the relevant responsible personnel shall be held accountable according to the law and regulations; Those suspected of committing a crime shall be transferred to judicial organs for handling.

Chapter V Supplementary Provisions

Article 32　　Other projects outside the fields of housing, municipal administration, railways, highways, waterways, civil aviation, water conservancy and communications shall be implemented with reference to these measures.

Where the wage guarantee is replaced by the guarantee company’s guarantee, it shall be implemented with reference to the relevant provisions of the bank guarantee.

Article 33　　These Measures shall be interpreted by the Provincial Department of Human Resources and Social Security in conjunction with the Provincial Development and Reform Commission, the Provincial Department of Housing and Urban-Rural Development, the Provincial Department of Transportation, the Provincial Department of Water Resources, the Provincial Communications Administration, the Hefei Central Branch of the People’s Bank of China, and the Anhui Supervision Bureau of China Banking and Insurance Regulatory Commission, China. Major problems encountered in the implementation, please report to the Provincial Department of Human Resources and Social Security in a timely manner.

Article 34　　These Measures shall come into force as of the date of promulgation.

Before the implementation of these Measures, the wage deposit, bank guarantee or guarantee insurance that has been stored according to the original wage deposit policy of the territory shall remain valid, and its daily management, use and return shall be implemented in accordance with the original provisions; After the implementation of these measures, the wage margin of newly started projects and projects under construction that have not yet stored the wage margin shall be implemented in accordance with these measures.

Attachment: 1. Deposit Agreement for Wage Margin of Migrant Workers (Sample)

2. Application Form for Differentiated Deposit of Wage Margin for Migrant Workers (Sample)

3 migrant workers’ wage margin differential deposit certificate (sample)

4 migrant workers’ wage deposit bank guarantee (sample)

5 migrant workers’ wage payment performance guarantee insurance certificate (sample)

6. Notice of Payment of Wage Margin for Migrant Workers (Sample)

7 migrant workers’ wage deposit return (cancellation) application form (sample)

8 migrant workers’ wage deposit return (cancellation) confirmation (sample)

Attachment 1-8.doc

　　More than 27,000 bilateral treaties, more than 500 multilateral treaties, 98% of land border issues have been solved, and 121 extradition and criminal judicial assistance treaties & HELIP; … This set of figures shows People’s Republic of China (PRC)’s great contribution to the construction of international law since its founding 70 years ago. The practice of 70 years shows that China has become an important force to defend international fairness and justice and promote the development of international law, and is an important participant, staunch defender and builder of international law.

　　"Since the founding of New China 70 years ago, China has not only resumed its legal seat in the United Nations and fully integrated into the international system, but also become an important participant, defender and builder of the international system with the United Nations as the core and international law as the foundation." Recently, Jia Guide, Director of the Treaty and Law Department of the Ministry of Foreign Affairs, said in an exclusive interview with the reporter of Legal Daily.

　　China has always adhered to the purposes and principles of the Charter of the United Nations, constructively participated in the formulation of international rules in various fields, and has become an important force in safeguarding international fairness and justice and promoting the development of international law.

Some treaties signed by the China government since the founding of New China 70 years ago. Photo courtesy of the Ministry of Foreign Affairs

　　More than 27,000 bilateral and multilateral treaties have been concluded.

　　On October 1st, 1949, People’s Republic of China (PRC) was founded.

　　"After the founding of People’s Republic of China (PRC), one of the first foreign legal affairs to be dealt with is to comprehensively clean up the treaties signed between the old government and foreign countries." Jia Guide said that according to the customary international law on treaty succession, the new government can not inherit the unequal treaties signed by foreign countries with the old government through illegal means such as war and coercion.

　　In September 1949, the first political consultative conference in China adopted the Common Program, which pointed out: "The Central People’s Government of People’s Republic of China (PRC) should review the treaties and agreements concluded between the Kuomintang government and foreign governments, and recognize them respectively, or abolish them, or modify them, or re-write them according to their contents."

　　On this basis, New China steadily cleaned up the old treaties, promoted the conclusion of new treaties with foreign countries, and formulated the Treaty Concluding Procedure Law in 1990. Up to now, China has concluded more than 27,000 bilateral treaties and more than 500 multilateral treaties, covering all aspects of international exchanges such as politics, economy, society and culture. A complete treaty system has laid a strong legal foundation for China’s opening up, exchanges and cooperation.

On December 31st, 1953, Premier Zhou Enlai put forward the Five Principles of Peaceful Coexistence for the first time when he met with the Indian government delegation. The picture shows Premier Zhou Enlai taking photos with Indian President Rajendra Prashad (first from right), Vice President sarvepalli radhakrishnan (third from right) and Prime Minister Jawaharlal Nehru (first from left) when he was invited to visit India in late June 1954. Information picture

　　Advocate and adhere to the Five Principles of Peaceful Coexistence

　　China has always advocated and adhered to the Five Principles of Peaceful Coexistence and made historic contributions to the development of international law.

　　In the 1950s, in the decolonization movement after the end of the Second World War, the cause of national independence and liberation in Asia, Africa and Latin America flourished, and newly independent countries were eager to establish equal international relations.

　　Following the historical trend, New China, together with India and Myanmar, advocated the five principles of mutual respect for sovereignty and territorial integrity, mutual non-aggression, non-interference in each other’s internal affairs, equality and mutual benefit, and peaceful coexistence in 1954. Over the past 60 years, the Five Principles have reflected the universal demands of developing countries for independence, independence, self-improvement and development, and also promoted exchanges and cooperation between countries with different ideologies and social systems.

　　"The Five Principles are highly consistent with the provisions of the Charter of the United Nations on friendly relations between countries, such as sovereign equality, non-use of force and non-interference in internal affairs. They have become the basic norms guiding state-to-state relations and the basic principles of international law, and have been widely recognized and followed by the international community." Jia Guide emphasized that the Five Principles have also been enshrined in the Constitution of China, as well as in the communiqué s on the establishment of diplomatic relations between China and more than 160 countries and bilateral treaties, which have become the cornerstone of China’s independent foreign policy of peace.

On July 1, 1997, at the handover ceremony, the flag-raising ceremony of China national flag was held. Photo by Wang Miao

　　The principle of "one country, two systems" enriches the development of international law

　　China also creatively put forward the policy of "one country, two systems" in order to properly solve the problems of Hong Kong and Macao left over from history.

　　According to the principle of "one country, two systems", China, Britain and Portugal reached a joint statement through peaceful negotiations, realizing China’s smooth resumption of the exercise of sovereignty over Hong Kong and Macao, which has become a model for peaceful settlement of historical issues between countries.

　　“‘ One country, two systems ’ Principles and practices have enriched and developed the specific system of international law. " Jia Guide said, for example, there are no ready-made practices and precedents to follow on how to solve the problem of applying and concluding treaties in Hong Kong and Macao Special Administrative Regions and how to implement "one country, two systems" and the Basic Law of the two Special Administrative Regions at the treaty level. In order to ensure the smooth development of foreign exchanges between Hong Kong and Macao Special Administrative Regions, the central government has initiated many new practices in this regard in accordance with the Basic Law. For example, the SAR is given a certain degree of right to conclude foreign treaties, and special arrangements are made for the application of multilateral treaties, taking into account the actual needs of the Hong Kong and Macao SAR, including allowing some treaties that have not yet been joined by the central government and were applied in Hong Kong and Macao before the reunification to continue to apply after the reunification, and some treaties that have been joined in the name of the central government are only applicable to Hong Kong and Macao. All these have enriched and developed international law.

　　Safeguard the country’s territorial sovereignty and maritime rights and interests

　　"China has demarcated and demarcated its borders with 12 of its 14 land neighbors in accordance with international law, and solved 98% of the land border problems." Jia Guide said.

　　On the basis of respecting historical facts and in accordance with international law, China insists on resolving disputes over territorial sovereignty and maritime delimitation through negotiations with the countries directly concerned, and has reached arrangements on maritime delimitation and fishery cooperation through negotiations with Japan, South Korea, Vietnam and other countries, resolutely and forcefully responding to the so-called arbitration against the South China Sea, and opposing any dispute settlement scheme imposed on China and the abuse of arbitration procedures to damage China’s sovereignty and maritime rights and interests.

　　Jia Guide emphasized that China creatively put forward the idea of "shelving disputes and jointly developing" and signed the Declaration on the Conduct of Parties in the South China Sea with ASEAN countries. At present, the consultation on formulating the Code of Conduct in the South China Sea has entered the fast lane.

　　Moreover, China has established and improved its domestic marine legislation in accordance with international law. Jia Guide said that shortly after the founding of New China, the China government issued the Declaration on the Territorial Sea, declaring that the width of China’s territorial sea is 12 nautical miles, and all foreign aircraft and military vessels are not allowed to enter China’s territorial sea and the territorial sea without the permission of the China government.

　　China’s related ideas and practices are not only consistent with the 1958 Convention on Territorial Seas and Adjoining Zones, but also with the development trend of international law at that time, which has played an important role in safeguarding national sovereignty, security and maritime rights and interests. China participated in the negotiation of the United Nations Convention on the Law of the Sea and its related implementation agreements, and formulated modern marine legal systems such as territorial sea and the contiguous zone, fishery law, exclusive economic zone and continental shelf law in accordance with international laws including the Convention.

　　Building an international judicial law enforcement cooperation network

　　At present, China has concluded 121 treaties on extradition and criminal judicial assistance with 74 countries, and it can be said that a system of treaties covering major countries in five continents has been initially established.

　　"Since the 18th National Congress of the Communist Party of China, we have focused on key pursuit targets, key pursuit countries and key contracting countries, built a treaty network, concluded 39 extradition and criminal judicial assistance treaties, and promoted the entry into force of 24 treaties, which is unprecedented in the history of treaty negotiation. Efforts and achievements." Jia Guide said, "We have achieved a breakthrough in the pursuit and recovery of important countries such as the European Union. Extradition treaties with France and Italy have come into effect one after another, and treaties on criminal judicial assistance have been concluded with Britain and Austria."

　　The China Municipal Government has actively and comprehensively established a legal network for international judicial and law enforcement cooperation, serving and promoting the comprehensive rule of law and the anti-corruption pursuit and recovery work. For example, China actively promotes the conclusion of bilateral extradition treaties and judicial assistance treaties with foreign countries, and participates in multilateral treaties such as the United Nations Convention against Transnational Organized Crime and the United Nations Convention against Corruption, providing legal support for promoting judicial law enforcement cooperation between China and foreign countries and international cooperation against corruption.

On April 22nd, 2016, local time, Zhang Gaoli, Special Envoy of the Supreme Leader of president, China and Deputy Prime Minister of the State Council, attended the high-level signing ceremony of the Paris Agreement at the United Nations Headquarters in new york, and signed the Paris Agreement on behalf of China. Xinhua news agency

　　Constructive participation in the formulation of global governance rules

　　"China is widely involved in international treaties and mechanisms related to global governance. It is an important participant and builder of global governance rules and has become a leader in some fields." Jia Guide said.

　　In the field of climate change, China, together with developing countries, promoted the principle of "common but differentiated responsibilities" to be written into the United Nations Framework Convention on Climate Change, promoted the adoption of the Kyoto Protocol, implemented the common zone principle, and made important contributions to the Paris Agreement.

　　China adheres to the principle of "common heritage of mankind" and actively participates in international seabed affairs. As early as 1990, COMRA of China applied for registration as one of the pioneer investors. So far, the International Seabed Authority has approved China’s application for five mining areas.

　　China has successively joined the Antarctic Treaty, the Convention on the Protection of Antarctic Marine Living Resources, the Protocol to the Antarctic Treaty on Environmental Protection and other treaty systems, and carried out Antarctic scientific research, fisheries and other activities in accordance with relevant treaties. As a negotiating country of the Antarctic Treaty and a member of the Antarctic Marine Living Resources Conservation Committee, it has fully participated in Antarctic governance. As an observer of the Arctic Council, China participates in Arctic affairs in accordance with international law and strives to contribute China wisdom and China’s strength to the development of the Arctic.

　　China has also actively promoted the formulation of rules in new areas of global governance such as the Internet and outer space, providing a legal basis for the orderly development of international cooperation.

　　□ Reporter’s Notes

　　"China will firmly uphold the international system with the United Nations as the core and based on international law, and persist in being a staunch defender and builder of international law."

　　This is the firm voice of Jia Guide, Director of the Treaty and Law Department of the Ministry of Foreign Affairs, after the interview.

　　In the 70-year historical process, China has always held high the banner of international law, adhered to the international law system centered on the purposes and principles of the Charter of the United Nations, constructively participated in the formulation of international rules in various fields, actively promoted the democratization of international relations, advocated the equal and unified application of international law, and stood up for its words on major international and regional issues, thus becoming the backbone of defending international fairness and justice and promoting the development of international law. As Chairman Supreme Leader pointed out when meeting with UN Secretary-General Guterres in April this year, "China firmly upholds multilateralism, the international system with the UN at the core, the international order based on international law, and promotes the building of a community of human destiny".

　　China embodies the following distinctive features in the practice of international law: First, it emphasizes respect for national sovereignty, upholds the sovereign equality of all countries, and opposes interfering in other countries’ internal affairs and infringing on their sovereignty under any pretext.

　　Second, we want peace instead of war, adhere to mutual non-aggression, oppose the frequent use or threat of force, advocate peaceful settlement of international disputes, and respect the right to freely choose dispute settlement methods.

　　Third, adhere to fairness and justice, advocate the equal and uniform application of international law, do not engage in double standards, and oppose "using it together, but abandoning it if it is not".

　　The fourth is to defend multilateralism, oppose unilateralism and bullying, and achieve mutual benefit and common development through international cooperation on the basis of equality.

　　At present, the international situation continues to fluctuate and the uncertainty is more prominent. In particular, individual countries pursue unilateralism and protectionism, violate international obligations, weaken multilateral mechanisms, engage in bullying and interference, impose unilateral sanctions indiscriminately, provoke trade wars and scientific and technological wars everywhere, and ignore the basic norms of international law and international relations, which has brought uneasiness, conflict and turmoil to the world.

　　Faced with this situation, on the one hand, China clearly adheres to multilateralism and firmly upholds the international system with the United Nations as the core and based on international law; on the other hand, it strengthens cooperation with other countries on the basis of the above principles, and works together to build a community of human destiny and build a new type of international relations.

　　The Chairman of the Supreme Leader has put forward an important initiative to build a community of human destiny on a series of international occasions. This concept has been written into the Constitution of China, which represents China’s solemn commitment to firmly follow the path of peaceful development and firmly safeguard international law.

　　Reporter Wang Yanyan

2014 is the "first year of self-making" for China video websites to concentrate on the field of self-made dramas. Compared with traditional TV dramas, how to truly create an Internet phenomenal super-online drama and open up a big online drama era beyond traditional TV dramas,Various video websites have invested the largest amount of capital and resources in the history in the direction of self-production. At present, the most powerful one is the "Hurry that Year" with a single investment of over one million.

After it was launched on August 4th, the youth online drama "In a hurry that year" quickly occupied the first place in all kinds of rankings of word of mouth and hot search, surpassing not only all online dramas, but also TV dramas such as swords of legends, Divorce Lawyer, Ten Years of Love and Obstetrician, which have been popular in TV stations recently.

The major search indexes ranked first.

The online drama "In a hurry that year" focuses on the theme of nostalgic youth, bringing the past youth growth of the post-80 s to the audience with the roles of Chen Xun, Fang Fen, Qiao Ran, Lin Jiamo and Zhao Ye. Although the online drama "In a hurry that year" is a memory story of the post-80s generation, it has also attracted the same drama-chasing craze. It can also be seen from the trend of Baidu index that the popularity of "In a hurry that year" has continued to climb since its first broadcast. Only seven days later, on August 11, Baidu index surpassed all online dramas in the same period and became the first. Looking at the 7-day overall increase rate of Baidu index, the overall year-on-year increase rate and mobile year-on-year increase rate of "In a hurry" both reached the peak of 1000%, and it is a new generation of self-made "drama king" in terms of growth momentum.

In a hurry that year, a weekly online drama, broke the boundary between online drama and TV drama, and brought online drama into a brand-new "big era". First of all, in terms of production cost, the input specification of each episode exceeds one million, which is already the production cost of first-line TV series; Secondly, in terms of shooting specifications, it is the first in China to apply 4K HD shooting technology to film and television drama shooting; In addition, film-level personnel and resources are invested in editing and publicity, and the promotion efforts have reached the peak of the online video industry. Unlike Divorce Lawyer, which was launched on the same day as the last drama, Hurriedly That Year represents a more subversive future.

High-level, high-standard, high-input, so that the fans of "In a hurry that year" are not disappointed. Late-stage, editing, sound effects and other large-scale productions, the difference only depends on the shortcomings of the star’s China TV drama industry, and the focus of the big online drama is subversive high quality. "In a hurry that year" received a large-scale investment of more than one million episodes, and pioneered the 4K high-definition shooting on the Internet. It has been compared with TV dramas in terms of pre-shooting, post-production, music sound effects, broadcasting platform and marketing, realizing the unprecedented all-round subversion of the Internet industry and opening the era of "big network drama" 4K high-definition drama viewing. Since its first broadcast on August 4th, "In a hurry that year" has continued to dominate the list of topics in Weibo in Weibo. Continuously boarded the hot list of topics in Weibo, hot TV series, film and television hot search list, etc.

　

Douban 8.1′ s high score beats TV drama.

"In a hurry that year" not only has a high attention craze, but also has high praise. On Douban, 8.1 points were scored in Rush Year, 7.1 points in swords of legends, 6.8 points in Divorce Lawyer and 7.9 points in Ten Years of Love … … The 8.1 points of "In a hurry that year" have surpassed some high-profile TV dramas.

Some netizens said: "My drama-following weekly schedule is finally full. I will follow" The Year of Hurriedness "on Monday and Tuesday, and" swords of legends "&hellip on Wednesday and Thursday; …” However, the actors in that year in a hurry are all "small fresh meat", which completely breaks the traditional rule of taking the drama with the stars and puts all the large investment in the repertoire on creating the quality of that year in a hurry. Although "In a hurry that year" and "Divorce Lawyer" are the same as satellite TV dramas with millions of investments, the actors in satellite TV dramas account for the vast majority, and the production may not be as good as "In a hurry that year".

　

Zero bad review and high recommendation

"In a hurry that year" held a national touring movie-watching activity in Beijing, Guangzhou, Shenyang, Chengdu and Zhengzhou. In five places, a group of media people and "in a hurry" fans can enjoy the "In a hurry" filmed by 4K ultra-high-definition technology in advance. As a result, in the process of touring movies, the repertoire evaluation with zero bad reviews and high recommendation rate of fans was obtained.

In the eyes of many media people, "In a hurry" not only triggered a wave of topics about the post-80 s youth, but also produced and filmed the drama’s 4K high-definition pictures, exquisite editing of big movies, role selection that fits the plot, which completely compared with the scale of the film’s announcement and completely refreshed the media people’s understanding of self-made online dramas. At the same time, the online drama "In a hurry that year" was also highly recommended by the famous writer Zhang Jiajia, which once again showed the high recognition of "In a hurry that year" in the industry.

　

"In a hurry that year" adopted the big movie-style announcement specification, which not only adopted the big movie specification in shooting and editing, but also allowed the audience in five places who watched the movie in advance to enjoy the brand-new enjoyment of watching the 4K high-definition online drama in the cinema. As far as the final audience watch drama questionnaire is concerned, "In a hurry that year" won no bad review score and a high recommendation rate of 99%.